- claim_text
Together, these results indicate that VIP+ INs in the Tcf4 +/ tr mice show increased input resistance and reduced frequency of sEPSCs which indicates the excitatory drive onto VIP+ INs is reduced, and this may be slightly counterbalanced by an increase sensitivity/responsiveness to synaptic inputs d
- raw_fields
{
"n": 0,
"doi": "10.1038/s41380-023-02248-z",
"claim": "Together, these results indicate that VIP+ INs in the Tcf4 +/ tr mice show increased input resistance and reduced frequency of sEPSCs which indicates the excitatory drive onto VIP+ INs is reduced, and this may be slightly counterbalanced by an increase sensitivity/responsiveness to synaptic inputs d",
"title": null,
"cite_key": "Chen2023b",
"evidence": "Reported in study using human, mouse, rat.",
"effect_size": null,
"text_access": "fulltext",
"study_system": "human, mouse, rat",
"_source_cluster": "cluster_10_species_disease",
"replication_status": "multiple_database_indexed",
"_source_cluster_index": 0,
"claim_source_sentence": "Together, these results indicate that VIP+ INs in the Tcf4 +/ tr mice show increased input resistance and reduced frequency of sEPSCs which indicates the excitatory drive onto VIP+ INs is reduced, and this may be slightly counterbalanced by an increase sensitivity/responsiveness to synaptic inputs due to the increased input resistance.",
"replication_evidence_dois": [],
"effect_size_source_sentence": null
}- source_refs
[
"paper:paper-bcba2772b0e0"
]
- source_span
Together, these results indicate that VIP+ INs in the Tcf4 +/ tr mice show increased input resistance and reduced frequency of sEPSCs which indicates the excitatory drive onto VIP+ INs is reduced, and this may be slightly counterbalanced by an increase sensitivity/responsiveness to synaptic inputs due to the increased input resistance.
- evidence_refs
[
{
"ref": "paper:paper-bcba2772b0e0"
}
]- source_policy
{
"mode": "public_source_pointer_with_short_context",
"notes": [
"Local review repositories are read-only inputs.",
"SciDEX stores paper metadata, structured evidence, file pointers, and short citation contexts; it does not copy full review prose."
],
"source_commit_sha": "95e761177f7d2ec565983d3307c14ec238f9677c",
"source_repository_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewVIP"
}