Version history

{
  "scope": "mouse cortex",
  "claim_text": "In triple transgenic mice we found that intralaminarly both PV and VIP IN effectively target L5 SST IN.",
  "raw_fields": {
    "n": 124,
    "doi": "10.1113/jp288309",
    "claim": "In triple transgenic mice we found that intralaminarly both PV and VIP IN effectively target L5 SST IN.",
    "evidence": "Layer (L) 5 is a hub in the cortical column in which a multitude of feedforward and feedback pathways converge. These inputs are then transmitted to distant sites by resident pyramidal neurons (PN). L5 PN are under the strong influence of local somatostatin (SST)-expressing interneurons (IN). To bet",
    "effect_size": "IPSC at 10× laser threshold amplitude was 352.7 ± 252.4 pA for PV inputs ( n = 11) and 254.2 ± 240.0 pA for VIP inputs ( n = 13, P = 0.3311, Mann–Whitney test, Fig.",
    "text_access": "fulltext",
    "study_system": "mouse cortex",
    "replication_status": "within_lab_replicated",
    "claim_source_sentence": "In triple transgenic mice we found that intralaminarly both PV and VIP IN effectively target L5 SST IN.",
    "replication_evidence_dois": [],
    "effect_size_source_sentence": "IPSC at 10× laser threshold amplitude was 352.7 ± 252.4 pA for PV inputs ( n = 11) and 254.2 ± 240.0 pA for VIP inputs ( n = 13, P = 0.3311, Mann–Whitney test, Fig."
  },
  "section_id": "section_06_evidence_package",
  "source_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewPV/blob/df9fc7e8d455b084152c9d713558dae0013cef21/evidence/section_06_evidence_package.json",
  "effect_size": "IPSC at 10× laser threshold amplitude was 352.7 ± 252.4 pA for PV inputs ( n = 11) and 254.2 ± 240.0 pA for VIP inputs ( n = 13, P = 0.3311, Mann–Whitney test, Fig.",
  "review_repo": "ComputationalReviewPV",
  "section_ref": "wiki_page:computationalreviewpv-06",
  "source_kind": "review_finding",
  "source_path": "evidence/section_06_evidence_package.json",
  "source_refs": [
    "paper:paper-737e539c1091"
  ],
  "source_span": "In triple transgenic mice we found that intralaminarly both PV and VIP IN effectively target L5 SST IN.",
  "study_system": "mouse cortex",
  "evidence_refs": [
    {
      "ref": "paper:paper-737e539c1091"
    }
  ],
  "section_title": "Synaptic Physiology: Input Specificity, Output Targeting, and Short-Term Dynamics",
  "source_policy": {
    "mode": "public_source_pointer_with_short_context",
    "notes": [
      "Local review repositories are read-only inputs.",
      "SciDEX stores paper metadata, structured evidence, file pointers, and short citation contexts; it does not copy full review prose."
    ],
    "source_commit_sha": "df9fc7e8d455b084152c9d713558dae0013cef21",
    "source_repository_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewPV"
  },
  "evidence_summary": "Layer (L) 5 is a hub in the cortical column in which a multitude of feedforward and feedback pathways converge. These inputs are then transmitted to distant sites by resident pyramidal neurons (PN). L5 PN are under the strong influence of local somatostatin (SST)-expressing interneurons (IN). To bet",
  "review_bundle_ref": "analysis_bundle:ab-e6261c8263e7",
  "replication_status": "within_lab_replicated",
  "review_package_ref": "analysis_bundle:ab-e6261c8263e7",
  "source_artifact_ref": "wiki_page:computationalreviewpv-06",
  "origin_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewPV/blob/df9fc7e8d455b084152c9d713558dae0013cef21/evidence/section_06_evidence_package.json",
  "commit_sha": "df9fc7e8d455b084152c9d713558dae0013cef21",
  "created_by": "persona-jerome-lecoq-gbo-neuroscience",
  "repository_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewPV"
}