Details

scope
mouse cortex
claim_text
In triple transgenic mice we found that intralaminarly both PV and VIP IN effectively target L5 SST IN.
section_id
section_06_evidence_package
source_url
https://github.com/AllenNeuralDynamics/ComputationalReviewPV/blob/df9fc7e8d455b084152c9d713558dae0013cef21/evidence/section_06_evidence_package.json
effect_size
IPSC at 10× laser threshold amplitude was 352.7 ± 252.4 pA for PV inputs ( n = 11) and 254.2 ± 240.0 pA for VIP inputs ( n = 13, P = 0.3311, Mann–Whitney test, Fig.
review_repo
ComputationalReviewPV
section_ref
wiki_page:computationalreviewpv-06
source_kind
review_finding
source_path
evidence/section_06_evidence_package.json
source_span
In triple transgenic mice we found that intralaminarly both PV and VIP IN effectively target L5 SST IN.
study_system
mouse cortex
section_title
Synaptic Physiology: Input Specificity, Output Targeting, and Short-Term Dynamics
review_bundle_ref
analysis_bundle:ab-e6261c8263e7
replication_status
within_lab_replicated
review_package_ref
analysis_bundle:ab-e6261c8263e7
source_artifact_ref
wiki_page:computationalreviewpv-06
origin_url
https://github.com/AllenNeuralDynamics/ComputationalReviewPV/blob/df9fc7e8d455b084152c9d713558dae0013cef21/evidence/section_06_evidence_package.json
commit_sha
df9fc7e8d455b084152c9d713558dae0013cef21
created_by
persona-jerome-lecoq-gbo-neuroscience
repository_url
https://github.com/AllenNeuralDynamics/ComputationalReviewPV
Raw fields (5)
raw_fields
{
  "n": 124,
  "doi": "10.1113/jp288309",
  "claim": "In triple transgenic mice we found that intralaminarly both PV and VIP IN effectively target L5 SST IN.",
  "evidence": "Layer (L) 5 is a hub in the cortical column in which a multitude of feedforward and feedback pathways converge. These inputs are then transmitted to distant sites by resident pyramidal neurons (PN). L5 PN are under the strong influence of local somatostatin (SST)-expressing interneurons (IN). To bet",
  "effect_size": "IPSC at 10× laser threshold amplitude was 352.7 ± 252.4 pA for PV inputs ( n = 11) and 254.2 ± 240.0 pA for VIP inputs ( n = 13, P = 0.3311, Mann–Whitney test, Fig.",
  "text_access": "fulltext",
  "study_system": "mouse cortex",
  "replication_status": "within_lab_replicated",
  "claim_source_sentence": "In triple transgenic mice we found that intralaminarly both PV and VIP IN effectively target L5 SST IN.",
  "replication_evidence_dois": [],
  "effect_size_source_sentence": "IPSC at 10× laser threshold amplitude was 352.7 ± 252.4 pA for PV inputs ( n = 11) and 254.2 ± 240.0 pA for VIP inputs ( n = 13, P = 0.3311, Mann–Whitney test, Fig."
}
source_refs
[
  "paper:paper-737e539c1091"
]
evidence_refs
[
  {
    "ref": "paper:paper-737e539c1091"
  }
]
source_policy
{
  "mode": "public_source_pointer_with_short_context",
  "notes": [
    "Local review repositories are read-only inputs.",
    "SciDEX stores paper metadata, structured evidence, file pointers, and short citation contexts; it does not copy full review prose."
  ],
  "source_commit_sha": "df9fc7e8d455b084152c9d713558dae0013cef21",
  "source_repository_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewPV"
}
evidence_summary
Layer (L) 5 is a hub in the cortical column in which a multitude of feedforward and feedback pathways converge. These inputs are then transmitted to distant sites by resident pyramidal neurons (PN). L5 PN are under the strong influence of local somatostatin (SST)-expressing interneurons (IN). To bet

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