Version history

{
  "scope": "mouse, marmoset, human primary motor cortex (BICCN)",
  "claim_text": "The BICCN multimodal census of mammalian primary motor cortex integrates single-cell transcriptomes, chromatin accessibility, DNA methylomes, spatially resolved transcriptomes, morpho-electrophysiology and cellular-resolution input-output mapping into a cross-species consensus taxonomy of cortical cell types.",
  "raw_fields": {
    "n": 0,
    "doi": "10.1038/s41586-021-03950-0",
    "claim": "The BICCN multimodal census of mammalian primary motor cortex integrates single-cell transcriptomes, chromatin accessibility, DNA methylomes, spatially resolved transcriptomes, morpho-electrophysiology and cellular-resolution input-output mapping into a cross-species consensus taxonomy of cortical cell types.",
    "cite_key": "BRAINInitiativeCellCensusNetworkBICCN2021",
    "evidence": "Coordinated multi-modal profiling and integration of single-cell genomics, MERFISH, Patch-seq, single-neuron reconstruction and viral connectomics in mouse M1 and homologous regions of marmoset and human.",
    "effect_size": "qualitative — unified multimodal taxonomy",
    "text_access": "abstract_only",
    "study_system": "mouse, marmoset, human primary motor cortex (BICCN)",
    "argument_role": "supporting",
    "replication_status": "independently_replicated",
    "claim_source_sentence": "This was achieved by coordinated large-scale analyses of single-cell transcriptomes, chromatin accessibility, DNA methylomes, spatially resolved single-cell transcriptomes, morphological and electrophysiological properties and cellular resolution input-output mapping, integrated through cross-modal computational analysis.",
    "source_provenance_status": "non_substring_match",
    "replication_evidence_dois": [
      "10.1038/s41586-018-0654-5",
      "10.1038/s41586-021-03500-8"
    ],
    "effect_size_source_sentence": null
  },
  "section_id": "section_07",
  "source_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewRecurrence/blob/79ce062d54a924ce05953ec90aa9d26044d2b48f/evidence/section_07_evidence_package.json",
  "effect_size": "qualitative — unified multimodal taxonomy",
  "review_repo": "ComputationalReviewRecurrence",
  "section_ref": "wiki_page:computationalreviewrecurrence-07-celltype-motifs",
  "source_kind": "review_finding",
  "source_path": "evidence/section_07_evidence_package.json",
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    "paper:paper-pm-34616075"
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  "source_span": "This was achieved by coordinated large-scale analyses of single-cell transcriptomes, chromatin accessibility, DNA methylomes, spatially resolved single-cell transcriptomes, morphological and electrophysiological properties and cellular resolution input-output mapping, integrated through cross-modal computational analysis.",
  "study_system": "mouse, marmoset, human primary motor cortex (BICCN)",
  "evidence_refs": [
    {
      "ref": "paper:paper-pm-34616075"
    }
  ],
  "section_title": "7. Cell-type-specific E→E motifs in mouse — IT vs PT vs CT pyramidal projection classes; L5 thick-tufted recurrence; Patch-seq and Allen mouse-cortex taxonomy intersections; transcriptomic-type-specific connectivity",
  "source_policy": {
    "mode": "public_source_pointer_with_short_context",
    "notes": [
      "Local review repositories are read-only inputs.",
      "SciDEX stores paper metadata, structured evidence, file pointers, and short citation contexts; it does not copy full review prose."
    ],
    "source_commit_sha": "79ce062d54a924ce05953ec90aa9d26044d2b48f",
    "source_repository_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewRecurrence"
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  "replication_status": "independently_replicated",
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  "source_artifact_ref": "wiki_page:computationalreviewrecurrence-07-celltype-motifs",
  "origin_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewRecurrence/blob/79ce062d54a924ce05953ec90aa9d26044d2b48f/evidence/section_07_evidence_package.json",
  "commit_sha": "79ce062d54a924ce05953ec90aa9d26044d2b48f",
  "created_by": "persona-jerome-lecoq-gbo-neuroscience",
  "repository_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewRecurrence"
}