Version history

{
  "scope": "mouse VISp Patch-seq",
  "claim_text": "Patch-seq electrophysiological 'subthreshold-2' principal component is highly correlated with input resistance (Pearson r = 0.90), and a separate 'subthreshold (normalized) 1' PC reflects sag amplitude during hyperpolarizing current — providing two orthogonal axes of intrinsic-property variation that can be regressed onto t-type identity.",
  "raw_fields": {
    "n": 4270,
    "doi": "10.1016/j.cell.2020.09.057",
    "claim": "Patch-seq electrophysiological 'subthreshold-2' principal component is highly correlated with input resistance (Pearson r = 0.90), and a separate 'subthreshold (normalized) 1' PC reflects sag amplitude during hyperpolarizing current — providing two orthogonal axes of intrinsic-property variation that can be regressed onto t-type identity.",
    "title": null,
    "cite_key": "Gouwens2020a",
    "evidence": "PCA over 4,200+ Patch-seq cells; principal-component-vs-feature correlations across all neurons (excitatory + inhibitory).",
    "effect_size": "sPC2 ↔ Rin: r = 0.90 (Pearson); sPC1(norm) ↔ sag",
    "text_access": "fulltext",
    "study_system": "mouse VISp Patch-seq",
    "_source_cluster": "cluster_04_intrinsic_electrophysiology",
    "replication_status": "replication_unknown",
    "_source_cluster_index": 28,
    "claim_source_sentence": "Many of the sPCs were strongly related to traditional electrophysiological features; for example, the “subthreshold 2” sPC was correlated with input resistance (Pearson’s r = 0.90), and the “subthreshold (normalized) 1” sPC reflected the amount of sag induced by hyperpolarizing current steps (lower ...).",
    "replication_evidence_dois": [],
    "effect_size_source_sentence": "the “subthreshold 2” sPC was correlated with input resistance (Pearson’s r = 0.90)"
  },
  "section_id": "section_05",
  "source_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewVIP/blob/95e761177f7d2ec565983d3307c14ec238f9677c/evidence/section_05_evidence_package.json",
  "effect_size": "sPC2 ↔ Rin: r = 0.90 (Pearson); sPC1(norm) ↔ sag",
  "review_repo": "ComputationalReviewVIP",
  "section_ref": "wiki_page:computationalreviewvip-05-electrophysiology",
  "source_kind": "review_finding",
  "source_path": "evidence/section_05_evidence_package.json",
  "source_refs": [
    "paper:paper-pm-33186530"
  ],
  "source_span": "Many of the sPCs were strongly related to traditional electrophysiological features; for example, the “subthreshold 2” sPC was correlated with input resistance (Pearson’s r = 0.90), and the “subthreshold (normalized) 1” sPC reflected the amount of sag induced by hyperpolarizing current steps (lower ...).",
  "study_system": "mouse VISp Patch-seq",
  "evidence_refs": [
    {
      "ref": "paper:paper-pm-33186530"
    }
  ],
  "section_title": "Intrinsic Electrophysiology",
  "source_policy": {
    "mode": "public_source_pointer_with_short_context",
    "notes": [
      "Local review repositories are read-only inputs.",
      "SciDEX stores paper metadata, structured evidence, file pointers, and short citation contexts; it does not copy full review prose."
    ],
    "source_commit_sha": "95e761177f7d2ec565983d3307c14ec238f9677c",
    "source_repository_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewVIP"
  },
  "evidence_summary": "PCA over 4,200+ Patch-seq cells; principal-component-vs-feature correlations across all neurons (excitatory + inhibitory).",
  "review_bundle_ref": "analysis_bundle:ab-2ce40c33e827",
  "replication_status": "replication_unknown",
  "review_package_ref": "analysis_bundle:ab-2ce40c33e827",
  "source_artifact_ref": "wiki_page:computationalreviewvip-05-electrophysiology",
  "origin_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewVIP/blob/95e761177f7d2ec565983d3307c14ec238f9677c/evidence/section_05_evidence_package.json",
  "commit_sha": "95e761177f7d2ec565983d3307c14ec238f9677c",
  "created_by": "persona-jerome-lecoq-gbo-neuroscience",
  "repository_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewVIP"
}