Details

scope
mouse barrel cortex, in vivo during behavior
section_id
section_07_evidence_package
source_url
https://github.com/AllenNeuralDynamics/ComputationalReviewPV/blob/df9fc7e8d455b084152c9d713558dae0013cef21/evidence/section_07_evidence_package.json
effect_size
Touch excited FS interneurons at short latency, followed by E neurons and SST neurons; VIP neurons only weakly modulated by touch
review_repo
ComputationalReviewPV
section_ref
wiki_page:computationalreviewpv-07
source_kind
review_finding
source_path
evidence/section_07_evidence_package.json
source_span
Together, FS neurons track thalamic input, mediating feedforward inhibition. SST neurons monitor local excitation, providing feedback inhibition. VIP neurons are activated by non-sensory inputs, disinhibiting E and FS neurons.
study_system
mouse barrel cortex, in vivo during behavior
section_title
Local Circuit Motifs: Perisomatic Inhibition, Feedback, and Feedforward
evidence_summary
In vivo electrophysiological recordings of defined interneuron types during whisker-dependent object localization task
review_bundle_ref
analysis_bundle:ab-e6261c8263e7
replication_status
independently replicated
review_package_ref
analysis_bundle:ab-e6261c8263e7
source_artifact_ref
wiki_page:computationalreviewpv-07
origin_url
https://github.com/AllenNeuralDynamics/ComputationalReviewPV/blob/df9fc7e8d455b084152c9d713558dae0013cef21/evidence/section_07_evidence_package.json
commit_sha
df9fc7e8d455b084152c9d713558dae0013cef21
created_by
persona-jerome-lecoq-gbo-neuroscience
repository_url
https://github.com/AllenNeuralDynamics/ComputationalReviewPV
Raw fields (5)
claim_text
During active tactile behavior, FS interneurons track thalamic input mediating feedforward inhibition, SST neurons monitor local excitation providing feedback inhibition, and VIP neurons are activated by non-sensory inputs disinhibiting excitatory and FS neurons
raw_fields
{
  "n": 0,
  "doi": "10.1016/j.neuron.2019.07.027",
  "claim": "During active tactile behavior, FS interneurons track thalamic input mediating feedforward inhibition, SST neurons monitor local excitation providing feedback inhibition, and VIP neurons are activated by non-sensory inputs disinhibiting excitatory and FS neurons",
  "evidence": "In vivo electrophysiological recordings of defined interneuron types during whisker-dependent object localization task",
  "effect_size": "Touch excited FS interneurons at short latency, followed by E neurons and SST neurons; VIP neurons only weakly modulated by touch",
  "text_access": "fulltext",
  "study_system": "mouse barrel cortex, in vivo during behavior",
  "replication_status": "independently replicated",
  "claim_source_sentence": "Together, FS neurons track thalamic input, mediating feedforward inhibition. SST neurons monitor local excitation, providing feedback inhibition. VIP neurons are activated by non-sensory inputs, disinhibiting E and FS neurons.",
  "replication_evidence_dois": [
    "10.1038/nature12676"
  ],
  "effect_size_source_sentence": "Touch excited fast-spiking (FS) interneurons at short latency, followed by activation of excitatory (E) neurons and somatostatin-expressing (SST) interneurons. Touch only weakly modulated vasoactive intestinal polypeptide-expressing (VIP) interneurons."
}
source_refs
[
  "paper:e5dc2921-2ba0-4d4f-a34c-67e2b13a356d"
]
evidence_refs
[
  {
    "ref": "paper:e5dc2921-2ba0-4d4f-a34c-67e2b13a356d"
  }
]
source_policy
{
  "mode": "public_source_pointer_with_short_context",
  "notes": [
    "Local review repositories are read-only inputs.",
    "SciDEX stores paper metadata, structured evidence, file pointers, and short citation contexts; it does not copy full review prose."
  ],
  "source_commit_sha": "df9fc7e8d455b084152c9d713558dae0013cef21",
  "source_repository_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewPV"
}

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