Version history

{
  "scope": "mouse barrel cortex, in vivo during behavior",
  "claim_text": "During active tactile behavior, FS interneurons track thalamic input mediating feedforward inhibition, SST neurons monitor local excitation providing feedback inhibition, and VIP neurons are activated by non-sensory inputs disinhibiting excitatory and FS neurons",
  "raw_fields": {
    "n": 0,
    "doi": "10.1016/j.neuron.2019.07.027",
    "claim": "During active tactile behavior, FS interneurons track thalamic input mediating feedforward inhibition, SST neurons monitor local excitation providing feedback inhibition, and VIP neurons are activated by non-sensory inputs disinhibiting excitatory and FS neurons",
    "evidence": "In vivo electrophysiological recordings of defined interneuron types during whisker-dependent object localization task",
    "effect_size": "Touch excited FS interneurons at short latency, followed by E neurons and SST neurons; VIP neurons only weakly modulated by touch",
    "text_access": "fulltext",
    "study_system": "mouse barrel cortex, in vivo during behavior",
    "replication_status": "independently replicated",
    "claim_source_sentence": "Together, FS neurons track thalamic input, mediating feedforward inhibition. SST neurons monitor local excitation, providing feedback inhibition. VIP neurons are activated by non-sensory inputs, disinhibiting E and FS neurons.",
    "replication_evidence_dois": [
      "10.1038/nature12676"
    ],
    "effect_size_source_sentence": "Touch excited fast-spiking (FS) interneurons at short latency, followed by activation of excitatory (E) neurons and somatostatin-expressing (SST) interneurons. Touch only weakly modulated vasoactive intestinal polypeptide-expressing (VIP) interneurons."
  },
  "section_id": "section_07_evidence_package",
  "source_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewPV/blob/df9fc7e8d455b084152c9d713558dae0013cef21/evidence/section_07_evidence_package.json",
  "effect_size": "Touch excited FS interneurons at short latency, followed by E neurons and SST neurons; VIP neurons only weakly modulated by touch",
  "review_repo": "ComputationalReviewPV",
  "section_ref": "wiki_page:computationalreviewpv-07",
  "source_kind": "review_finding",
  "source_path": "evidence/section_07_evidence_package.json",
  "source_refs": [
    "paper:e5dc2921-2ba0-4d4f-a34c-67e2b13a356d"
  ],
  "source_span": "Together, FS neurons track thalamic input, mediating feedforward inhibition. SST neurons monitor local excitation, providing feedback inhibition. VIP neurons are activated by non-sensory inputs, disinhibiting E and FS neurons.",
  "study_system": "mouse barrel cortex, in vivo during behavior",
  "evidence_refs": [
    {
      "ref": "paper:e5dc2921-2ba0-4d4f-a34c-67e2b13a356d"
    }
  ],
  "section_title": "Local Circuit Motifs: Perisomatic Inhibition, Feedback, and Feedforward",
  "source_policy": {
    "mode": "public_source_pointer_with_short_context",
    "notes": [
      "Local review repositories are read-only inputs.",
      "SciDEX stores paper metadata, structured evidence, file pointers, and short citation contexts; it does not copy full review prose."
    ],
    "source_commit_sha": "df9fc7e8d455b084152c9d713558dae0013cef21",
    "source_repository_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewPV"
  },
  "evidence_summary": "In vivo electrophysiological recordings of defined interneuron types during whisker-dependent object localization task",
  "review_bundle_ref": "analysis_bundle:ab-e6261c8263e7",
  "replication_status": "independently replicated",
  "review_package_ref": "analysis_bundle:ab-e6261c8263e7",
  "source_artifact_ref": "wiki_page:computationalreviewpv-07",
  "origin_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewPV/blob/df9fc7e8d455b084152c9d713558dae0013cef21/evidence/section_07_evidence_package.json",
  "commit_sha": "df9fc7e8d455b084152c9d713558dae0013cef21",
  "created_by": "persona-jerome-lecoq-gbo-neuroscience",
  "repository_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewPV"
}