Version history

{
  "scope": "awake mouse barrel cortex; simultaneous electrophysiology + 2P calcium imaging through transparent NeuroGrids",
  "claim_text": "Touch-evoked translaminar dynamics in awake mouse barrel cortex are organized as a fast early component followed by a sparse late wave in L2/3 aligned to L5 apical dendritic Ca2+ events — a translaminar 'spacetime code' that depends on cortical feedback and is reconciled by an inhibition-stabilized balanced-state model.",
  "raw_fields": {
    "n": 0,
    "doi": "10.1126/sciadv.adr4038",
    "claim": "Touch-evoked translaminar dynamics in awake mouse barrel cortex are organized as a fast early component followed by a sparse late wave in L2/3 aligned to L5 apical dendritic Ca2+ events — a translaminar 'spacetime code' that depends on cortical feedback and is reconciled by an inhibition-stabilized balanced-state model.",
    "cite_key": "Gonzales2025",
    "evidence": "Simultaneous NeuroGrid electrophysiology + 2P calcium imaging in awake mouse barrel cortex during whisker touch.",
    "effect_size": "Late translaminar wave aligned to L5 apical dendritic Ca2+ events; modulated by cortical feedback.",
    "text_access": "abstract_only",
    "study_system": "awake mouse barrel cortex; simultaneous electrophysiology + 2P calcium imaging through transparent NeuroGrids",
    "argument_role": "supporting",
    "replication_status": "replication_unknown",
    "claim_source_sentence": "We found that the late wave feature was (i) modulated by motor feedback, (ii) differentially engaged a sparse ensemble reactivation pattern across layer 2/3, which a balanced-state network model reconciled via feedback-induced inhibitory stabilization, and (iii) aligned to regenerative layer 5 apical dendritic Caevents.",
    "source_provenance_status": "non_substring_match",
    "replication_evidence_dois": [],
    "effect_size_source_sentence": null
  },
  "section_id": "section_04",
  "source_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewRecurrence/blob/79ce062d54a924ce05953ec90aa9d26044d2b48f/evidence/section_04_evidence_package.json",
  "effect_size": "Late translaminar wave aligned to L5 apical dendritic Ca2+ events; modulated by cortical feedback.",
  "review_repo": "ComputationalReviewRecurrence",
  "section_ref": "wiki_page:computationalreviewrecurrence-04-translaminar",
  "source_kind": "review_finding",
  "source_path": "evidence/section_04_evidence_package.json",
  "source_refs": [
    "paper:paper-859009465eec"
  ],
  "source_span": "We found that the late wave feature was (i) modulated by motor feedback, (ii) differentially engaged a sparse ensemble reactivation pattern across layer 2/3, which a balanced-state network model reconciled via feedback-induced inhibitory stabilization, and (iii) aligned to regenerative layer 5 apical dendritic Caevents.",
  "study_system": "awake mouse barrel cortex; simultaneous electrophysiology + 2P calcium imaging through transparent NeuroGrids",
  "evidence_refs": [
    {
      "ref": "paper:paper-859009465eec"
    }
  ],
  "section_title": "4. Translaminar excitatory loops in mouse — L4→L2/3→L5→L6→L4 within the column; asymmetry of forward and backward intracortical projections",
  "source_policy": {
    "mode": "public_source_pointer_with_short_context",
    "notes": [
      "Local review repositories are read-only inputs.",
      "SciDEX stores paper metadata, structured evidence, file pointers, and short citation contexts; it does not copy full review prose."
    ],
    "source_commit_sha": "79ce062d54a924ce05953ec90aa9d26044d2b48f",
    "source_repository_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewRecurrence"
  },
  "evidence_summary": "Simultaneous NeuroGrid electrophysiology + 2P calcium imaging in awake mouse barrel cortex during whisker touch.",
  "review_bundle_ref": "analysis_bundle:ab-d9c479db9be9",
  "replication_status": "replication_unknown",
  "review_package_ref": "analysis_bundle:ab-d9c479db9be9",
  "source_artifact_ref": "wiki_page:computationalreviewrecurrence-04-translaminar",
  "origin_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewRecurrence/blob/79ce062d54a924ce05953ec90aa9d26044d2b48f/evidence/section_04_evidence_package.json",
  "commit_sha": "79ce062d54a924ce05953ec90aa9d26044d2b48f",
  "created_by": "persona-jerome-lecoq-gbo-neuroscience",
  "repository_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewRecurrence"
}