Version history

{
  "scope": "mouse PFC/hippocampus",
  "claim_text": "Figure 4 VIP Interneurons Disinhibit Prefrontal Responses to Hippocampal Inputs (A) Top, left: experimental design for in vitro patch-clamp experiments.",
  "raw_fields": {
    "n": 5,
    "doi": "10.1016/j.neuron.2019.04.001",
    "year": "2019",
    "claim": "Figure 4 VIP Interneurons Disinhibit Prefrontal Responses to Hippocampal Inputs (A) Top, left: experimental design for in vitro patch-clamp experiments.",
    "title": null,
    "journal": "Neuron",
    "cite_key": "Lee2019",
    "evidence": "VIP Interneurons Contribute to Avoidance Behavior by Regulating Information Flow across Hippocampal-Prefrontal Networks",
    "effect_size": null,
    "text_access": "fulltext",
    "first_author": "Lee",
    "study_system": "mouse PFC/hippocampus",
    "_source_cluster": "cluster_06_disinhibition_circuit",
    "author_list_short": "Lee, Cunniff, See",
    "replication_status": "replication_unknown",
    "_source_cluster_index": 34,
    "claim_source_sentence": "Figure 4 VIP Interneurons Disinhibit Prefrontal Responses to Hippocampal Inputs (A) Top, left: experimental design for in vitro patch-clamp experiments.",
    "replication_evidence_dois": [],
    "effect_size_source_sentence": "VIP GCaMP signals were highest in the center for a mouse that did not explore the open arms (left); for a mouse that did explore the open arms, VIP GCaMP signals were highest in the open arms (right). (D) Distributions of VIP-GCaMP signals (dF/F0) in different EPM zones: the closed arms (blue); center zone (green); or open arms (red) (n = 5 mice). (E) An example trace showing VIP-GCaMP signals during EPM exploration."
  },
  "section_id": "section_07",
  "source_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewVIP/blob/95e761177f7d2ec565983d3307c14ec238f9677c/evidence/section_07_evidence_package.json",
  "effect_size": null,
  "review_repo": "ComputationalReviewVIP",
  "section_ref": "wiki_page:computationalreviewvip-07-disinhibition-framework",
  "source_kind": "review_finding",
  "source_path": "evidence/section_07_evidence_package.json",
  "source_refs": [
    "paper:paper-bec295b7a9a9"
  ],
  "source_span": "Figure 4 VIP Interneurons Disinhibit Prefrontal Responses to Hippocampal Inputs (A) Top, left: experimental design for in vitro patch-clamp experiments.",
  "study_system": "mouse PFC/hippocampus",
  "evidence_refs": [
    {
      "ref": "paper:paper-bec295b7a9a9"
    }
  ],
  "section_title": "Local Circuit Motifs and the Disinhibition Framework",
  "source_policy": {
    "mode": "public_source_pointer_with_short_context",
    "notes": [
      "Local review repositories are read-only inputs.",
      "SciDEX stores paper metadata, structured evidence, file pointers, and short citation contexts; it does not copy full review prose."
    ],
    "source_commit_sha": "95e761177f7d2ec565983d3307c14ec238f9677c",
    "source_repository_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewVIP"
  },
  "evidence_summary": "VIP Interneurons Contribute to Avoidance Behavior by Regulating Information Flow across Hippocampal-Prefrontal Networks",
  "review_bundle_ref": "analysis_bundle:ab-2ce40c33e827",
  "replication_status": "replication_unknown",
  "review_package_ref": "analysis_bundle:ab-2ce40c33e827",
  "source_artifact_ref": "wiki_page:computationalreviewvip-07-disinhibition-framework",
  "origin_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewVIP/blob/95e761177f7d2ec565983d3307c14ec238f9677c/evidence/section_07_evidence_package.json",
  "commit_sha": "95e761177f7d2ec565983d3307c14ec238f9677c",
  "created_by": "persona-jerome-lecoq-gbo-neuroscience",
  "repository_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewVIP"
}