Details

scope
mouse PFC/hippocampus
claim_text
Figure 4 VIP Interneurons Disinhibit Prefrontal Responses to Hippocampal Inputs (A) Top, left: experimental design for in vitro patch-clamp experiments.
section_id
section_07
source_url
https://github.com/AllenNeuralDynamics/ComputationalReviewVIP/blob/95e761177f7d2ec565983d3307c14ec238f9677c/evidence/section_07_evidence_package.json
review_repo
ComputationalReviewVIP
section_ref
wiki_page:computationalreviewvip-07-disinhibition-framework
source_kind
review_finding
source_path
evidence/section_07_evidence_package.json
source_span
Figure 4 VIP Interneurons Disinhibit Prefrontal Responses to Hippocampal Inputs (A) Top, left: experimental design for in vitro patch-clamp experiments.
study_system
mouse PFC/hippocampus
section_title
Local Circuit Motifs and the Disinhibition Framework
evidence_summary
VIP Interneurons Contribute to Avoidance Behavior by Regulating Information Flow across Hippocampal-Prefrontal Networks
review_bundle_ref
analysis_bundle:ab-2ce40c33e827
replication_status
replication_unknown
review_package_ref
analysis_bundle:ab-2ce40c33e827
source_artifact_ref
wiki_page:computationalreviewvip-07-disinhibition-framework
origin_url
https://github.com/AllenNeuralDynamics/ComputationalReviewVIP/blob/95e761177f7d2ec565983d3307c14ec238f9677c/evidence/section_07_evidence_package.json
commit_sha
95e761177f7d2ec565983d3307c14ec238f9677c
created_by
persona-jerome-lecoq-gbo-neuroscience
repository_url
https://github.com/AllenNeuralDynamics/ComputationalReviewVIP
Raw fields (4)
raw_fields
{
  "n": 5,
  "doi": "10.1016/j.neuron.2019.04.001",
  "year": "2019",
  "claim": "Figure 4 VIP Interneurons Disinhibit Prefrontal Responses to Hippocampal Inputs (A) Top, left: experimental design for in vitro patch-clamp experiments.",
  "title": null,
  "journal": "Neuron",
  "cite_key": "Lee2019",
  "evidence": "VIP Interneurons Contribute to Avoidance Behavior by Regulating Information Flow across Hippocampal-Prefrontal Networks",
  "effect_size": null,
  "text_access": "fulltext",
  "first_author": "Lee",
  "study_system": "mouse PFC/hippocampus",
  "_source_cluster": "cluster_06_disinhibition_circuit",
  "author_list_short": "Lee, Cunniff, See",
  "replication_status": "replication_unknown",
  "_source_cluster_index": 34,
  "claim_source_sentence": "Figure 4 VIP Interneurons Disinhibit Prefrontal Responses to Hippocampal Inputs (A) Top, left: experimental design for in vitro patch-clamp experiments.",
  "replication_evidence_dois": [],
  "effect_size_source_sentence": "VIP GCaMP signals were highest in the center for a mouse that did not explore the open arms (left); for a mouse that did explore the open arms, VIP GCaMP signals were highest in the open arms (right). (D) Distributions of VIP-GCaMP signals (dF/F0) in different EPM zones: the closed arms (blue); center zone (green); or open arms (red) (n = 5 mice). (E) An example trace showing VIP-GCaMP signals during EPM exploration."
}
source_refs
[
  "paper:paper-bec295b7a9a9"
]
evidence_refs
[
  {
    "ref": "paper:paper-bec295b7a9a9"
  }
]
source_policy
{
  "mode": "public_source_pointer_with_short_context",
  "notes": [
    "Local review repositories are read-only inputs.",
    "SciDEX stores paper metadata, structured evidence, file pointers, and short citation contexts; it does not copy full review prose."
  ],
  "source_commit_sha": "95e761177f7d2ec565983d3307c14ec238f9677c",
  "source_repository_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewVIP"
}

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