Details
- scope
- mouse V1 L2/3 vs L5 pyramidal neurons
- claim_text
- In mouse V1, L2/3 pyramidal neurons require substantially more excitatory synaptic input to reach action-potential threshold than L5 pyramidal neurons, consistent with their lower in-vivo firing rates.
- section_id
- section_04
- source_url
- https://github.com/AllenNeuralDynamics/ComputationalReviewRecurrence/blob/79ce062d54a924ce05953ec90aa9d26044d2b48f/evidence/section_04_evidence_package.json
- effect_size
- higher input requirement in L2/3 vs L5 (qualitative)
- review_repo
- ComputationalReviewRecurrence
- section_ref
- wiki_page:computationalreviewrecurrence-04-translaminar
- source_kind
- review_finding
- source_path
- evidence/section_04_evidence_package.json
- source_span
- Layer 2/3 pyramidal neurons may therefore require substantially more excitatory synaptic input to drive them to action potential threshold compared with L5 pyramidal neurons.
- study_system
- mouse V1 L2/3 vs L5 pyramidal neurons
- section_title
- 4. Translaminar excitatory loops in mouse — L4→L2/3→L5→L6→L4 within the column; asymmetry of forward and backward intracortical projections
- evidence_summary
- Multi-shank silicon-probe recordings combined with biophysical inference across V1 layers in behaving mice.
- review_bundle_ref
- analysis_bundle:ab-d9c479db9be9
- replication_status
- replication_unknown
- review_package_ref
- analysis_bundle:ab-d9c479db9be9
- source_artifact_ref
- wiki_page:computationalreviewrecurrence-04-translaminar
- origin_url
- https://github.com/AllenNeuralDynamics/ComputationalReviewRecurrence/blob/79ce062d54a924ce05953ec90aa9d26044d2b48f/evidence/section_04_evidence_package.json
- commit_sha
- 79ce062d54a924ce05953ec90aa9d26044d2b48f
- created_by
- persona-jerome-lecoq-gbo-neuroscience
- repository_url
- https://github.com/AllenNeuralDynamics/ComputationalReviewRecurrence
Raw fields (4)
- raw_fields
{ "n": 0, "doi": "10.1016/j.neuron.2018.12.009", "claim": "In mouse V1, L2/3 pyramidal neurons require substantially more excitatory synaptic input to reach action-potential threshold than L5 pyramidal neurons, consistent with their lower in-vivo firing rates.", "cite_key": "Senzai2019", "evidence": "Multi-shank silicon-probe recordings combined with biophysical inference across V1 layers in behaving mice.", "effect_size": "higher input requirement in L2/3 vs L5 (qualitative)", "text_access": "fulltext", "study_system": "mouse V1 L2/3 vs L5 pyramidal neurons", "argument_role": "supporting", "replication_status": "replication_unknown", "claim_source_sentence": "Layer 2/3 pyramidal neurons may therefore require substantially more excitatory synaptic input to drive them to action potential threshold compared with L5 pyramidal neurons.", "source_provenance_status": "ok", "replication_evidence_dois": [], "effect_size_source_sentence": null }- source_refs
[ "paper:paper-2542771c593d" ]
- evidence_refs
[ { "ref": "paper:paper-2542771c593d" } ]- source_policy
{ "mode": "public_source_pointer_with_short_context", "notes": [ "Local review repositories are read-only inputs.", "SciDEX stores paper metadata, structured evidence, file pointers, and short citation contexts; it does not copy full review prose." ], "source_commit_sha": "79ce062d54a924ce05953ec90aa9d26044d2b48f", "source_repository_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewRecurrence" }