Beta1-adrenoceptors are expressed on PV interneurons in primate dlPFC; beta1-AR…

{
  "n": 0,
  "doi": "10.1016/j.ynstr.2024.100628",
  "claim": "Beta1-adrenoceptors are expressed on PV interneurons in primate dlPFC; beta1-AR agonist has mixed effects on fast-spiking neuron firing during working memory, and beta1-AR antagonism prevents stress-induced working memory deficits",
  "evidence": "Beta1-adrenoceptors are expressed on PV interneurons in primate dlPFC; beta1-AR agonist has mixed effects on fast-spiking neuron firing during working memory, and beta1-AR antagonism prevents stress-induced working memory deficits",
  "effect_size": "Beta1-adrenoceptors are expressed on PV interneurons in primate dlPFC; beta1-AR agonist has mixed effects on fast-spiking neuron firing during working memory, and beta1-AR antagonism prevents stress-i",
  "text_access": "fulltext",
  "study_system": "macaque dorsolateral prefrontal cortex, in vivo iontophoresis",
  "replication_status": "replication_unknown",
  "claim_source_sentence": "PV interneurons can be identified as fast-spiking (FS) in physiological recordings, and thus were studied in macaques performing a working memory task. Iontophoresis of a β1-AR agonist had a mixed effect, increasing the firing of a subset and decreasing the firing of others, likely reflecting loss of firing of the entire microcircuit.",
  "replication_evidence_dois": [],
  "effect_size_source_sentence": "PV interneurons can be identified as fast-spiking (FS) in physiological recordings, and thus were studied in macaques performing a working memory task. Iontophoresis of a β1-AR agonist had a mixed effect, increasing the firing of a subset and decreasing the firing of others, likely reflecting loss of firing of the entire microcircuit."
}

[
  "paper:paper-fff3aaa31d0b"
]

PV interneurons can be identified as fast-spiking (FS) in physiological recordings, and thus were studied in macaques performing a working memory task. Iontophoresis of a β1-AR agonist had a mixed effect, increasing the firing of a subset and decreasing the firing of others, likely reflecting loss of firing of the entire microcircuit.

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