- claim_text
In mouse hand/forelimb sensorimotor cortex, the corticocortical leg of the transcortical loop is dominated by S1 L2/3 and L5A neurons projecting to M1 L2/3 neurons that in turn excite corticospinal neurons — establishing a defined polysynaptic L2/3→L5 motif across areas.
- raw_fields
{
"n": 0,
"doi": "10.7554/elife.66836",
"claim": "In mouse hand/forelimb sensorimotor cortex, the corticocortical leg of the transcortical loop is dominated by S1 L2/3 and L5A neurons projecting to M1 L2/3 neurons that in turn excite corticospinal neurons — establishing a defined polysynaptic L2/3→L5 motif across areas.",
"cite_key": "Yamawaki2021",
"evidence": "Optogenetic circuit mapping along the cuneate→VPL→S1→M1 pathway in mouse hand/forelimb.",
"effect_size": "S1→M1 input lands chiefly on M1 L2/3, which excites M1 L5B corticospinal neurons.",
"text_access": "abstract_only",
"study_system": "mouse hand/forelimb S1 and M1; opto-circuit mapping along transcortical loop",
"argument_role": "supporting",
"replication_status": "replication_unknown",
"claim_source_sentence": "In the corticocortical leg, S1→M1 connections from L2/3 and L5A neurons mainly excited downstream L2/3 neurons, which excite corticospinal neurons.",
"source_provenance_status": "non_substring_match",
"replication_evidence_dois": [],
"effect_size_source_sentence": null
}- source_refs
[
"paper:paper-15b98c6c015d"
]
- evidence_refs
[
{
"ref": "paper:paper-15b98c6c015d"
}
]- source_policy
{
"mode": "public_source_pointer_with_short_context",
"notes": [
"Local review repositories are read-only inputs.",
"SciDEX stores paper metadata, structured evidence, file pointers, and short citation contexts; it does not copy full review prose."
],
"source_commit_sha": "79ce062d54a924ce05953ec90aa9d26044d2b48f",
"source_repository_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewRecurrence"
}