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- Live5/17/2026, 4:35:28 PM
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{ "scope": "mouse cortico-basal ganglia-thalamic mesoscale tracing", "claim_text": "High-resolution mesoscale mapping in mouse delineates six parallel cortico–basal ganglia–thalamic subnetworks, each closing back onto its originating corticostriatal neurons.", "raw_fields": { "n": 0, "doi": "10.1038/s41586-021-03993-3", "claim": "High-resolution mesoscale mapping in mouse delineates six parallel cortico–basal ganglia–thalamic subnetworks, each closing back onto its originating corticostriatal neurons.", "cite_key": "Foster2021", "evidence": "Whole-brain anterograde tracing parsed dorsal striatum into domains and traced their multisynaptic outputs through GPe, SNr, thalamic nuclei back to cortex; six closed parallel subnetworks emerged in mouse, with thalamic domains relaying back to the originating corticostriatal neurons.", "effect_size": "6 subnetworks; 14 SNr domains; 36 GPe domains; 29 striatal domains", "text_access": "fulltext", "study_system": "mouse cortico-basal ganglia-thalamic mesoscale tracing", "source_cluster_id": "cluster_06", "replication_status": "replication_unknown", "claim_source_sentence": "Subsequently, we identify six parallel cortico–basal ganglia–thalamic subnetworks that sequentially transduce specific subsets of cortical information through every elemental node of the cortico–basal ganglia–thalamic loop.", "replication_evidence_dois": [], "effect_size_source_sentence": "Accordingly, we identify 14 SNr and 36 GPe domains and a direct cortico-SNr projection." }, "section_id": "section_07", "source_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewLoops/blob/0632aae8abc141909207fe91f6349b9e36489c3b/evidence/section_07_evidence_package.json", "effect_size": "6 subnetworks; 14 SNr domains; 36 GPe domains; 29 striatal domains", "review_repo": "ComputationalReviewLoops", "section_ref": "wiki_page:computationalreviewloops-07", "source_kind": "review_finding", "source_path": "evidence/section_07_evidence_package.json", "source_refs": [ "paper:paper-79995db40fc1" ], "source_span": "Subsequently, we identify six parallel cortico–basal ganglia–thalamic subnetworks that sequentially transduce specific subsets of cortical information through every elemental node of the cortico–basal ganglia–thalamic loop.", "study_system": "mouse cortico-basal ganglia-thalamic mesoscale tracing", "evidence_refs": [ { "ref": "paper:paper-79995db40fc1" } ], "section_title": "Parallel Loop Channels: Motor, Limbic, Associative, and Beyond the Classic Three", "source_policy": { "mode": "public_source_pointer_with_short_context", "notes": [ "Local review repositories are read-only inputs.", "SciDEX stores paper metadata, structured evidence, file pointers, and short citation contexts; it does not copy full review prose." ], "source_commit_sha": "0632aae8abc141909207fe91f6349b9e36489c3b", "source_repository_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewLoops" }, "evidence_summary": "Whole-brain anterograde tracing parsed dorsal striatum into domains and traced their multisynaptic outputs through GPe, SNr, thalamic nuclei back to cortex; six closed parallel subnetworks emerged in mouse, with thalamic domains relaying back to the originating corticostriatal neurons.", "review_bundle_ref": "analysis_bundle:ab-d49e54403ef9", "replication_status": "replication_unknown", "review_package_ref": "analysis_bundle:ab-d49e54403ef9", "source_artifact_ref": "wiki_page:computationalreviewloops-07", "origin_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewLoops/blob/0632aae8abc141909207fe91f6349b9e36489c3b/evidence/section_07_evidence_package.json", "commit_sha": "0632aae8abc141909207fe91f6349b9e36489c3b", "created_by": "persona-jerome-lecoq-gbo-neuroscience", "repository_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewLoops" }