Version history

{
  "scope": "mouse vibrissal M1, S1 barrel cortex, and S2; laminar circuit mapping via glutamate uncaging in acute slices",
  "claim_text": "In mouse vM1, vS1, and S2, laminar maps of excitatory local circuits converge on a prominent descending pathway from L2/3→L5, with the L2/3→L5 connection the most conserved across areas.",
  "raw_fields": {
    "n": 0,
    "doi": "10.1371/journal.pbio.1000572",
    "claim": "In mouse vM1, vS1, and S2, laminar maps of excitatory local circuits converge on a prominent descending pathway from L2/3→L5, with the L2/3→L5 connection the most conserved across areas.",
    "cite_key": "Hooks2011",
    "evidence": "Glutamate uncaging and laser-scanning photostimulation laminar mapping in mouse vM1, vS1 barrel, and S2.",
    "effect_size": "Conserved L2/3→L5; variable L4→L2/3 and L6 pathways (relative strength matrices in paper).",
    "text_access": "abstract_only",
    "study_system": "mouse vibrissal M1, S1 barrel cortex, and S2; laminar circuit mapping via glutamate uncaging in acute slices",
    "argument_role": "supporting",
    "replication_status": "independently_replicated",
    "claim_source_sentence": "In vM1, the strongest projection was L2/3→L5. In vS1, strong projections were L2/3→L5 and L4→L3. L6 input and output were weak in both areas. In S2, L2/3→L5 exceeded the strength of the ascending L4→L3 projection, and local input to L6 was prominent. The most conserved pathways were L2/3→L5, and the most variable were L4→L2/3 and pathways involving L6.",
    "source_provenance_status": "non_substring_match",
    "replication_evidence_dois": [
      "10.1016/j.neuron.2008.12.020",
      "10.7554/eLife.71103"
    ],
    "effect_size_source_sentence": null
  },
  "section_id": "section_04",
  "source_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewRecurrence/blob/79ce062d54a924ce05953ec90aa9d26044d2b48f/evidence/section_04_evidence_package.json",
  "effect_size": "Conserved L2/3→L5; variable L4→L2/3 and L6 pathways (relative strength matrices in paper).",
  "review_repo": "ComputationalReviewRecurrence",
  "section_ref": "wiki_page:computationalreviewrecurrence-04-translaminar",
  "source_kind": "review_finding",
  "source_path": "evidence/section_04_evidence_package.json",
  "source_refs": [
    "paper:82e14b69-8c1b-41b8-b15b-f103a44caf3f"
  ],
  "source_span": "In vM1, the strongest projection was L2/3→L5. In vS1, strong projections were L2/3→L5 and L4→L3. L6 input and output were weak in both areas. In S2, L2/3→L5 exceeded the strength of the ascending L4→L3 projection, and local input to L6 was prominent. The most conserved pathways were L2/3→L5, and the most variable were L4→L2/3 and pathways involving L6.",
  "study_system": "mouse vibrissal M1, S1 barrel cortex, and S2; laminar circuit mapping via glutamate uncaging in acute slices",
  "evidence_refs": [
    {
      "ref": "paper:82e14b69-8c1b-41b8-b15b-f103a44caf3f"
    }
  ],
  "section_title": "4. Translaminar excitatory loops in mouse — L4→L2/3→L5→L6→L4 within the column; asymmetry of forward and backward intracortical projections",
  "source_policy": {
    "mode": "public_source_pointer_with_short_context",
    "notes": [
      "Local review repositories are read-only inputs.",
      "SciDEX stores paper metadata, structured evidence, file pointers, and short citation contexts; it does not copy full review prose."
    ],
    "source_commit_sha": "79ce062d54a924ce05953ec90aa9d26044d2b48f",
    "source_repository_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewRecurrence"
  },
  "evidence_summary": "Glutamate uncaging and laser-scanning photostimulation laminar mapping in mouse vM1, vS1 barrel, and S2.",
  "review_bundle_ref": "analysis_bundle:ab-d9c479db9be9",
  "replication_status": "independently_replicated",
  "review_package_ref": "analysis_bundle:ab-d9c479db9be9",
  "source_artifact_ref": "wiki_page:computationalreviewrecurrence-04-translaminar",
  "origin_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewRecurrence/blob/79ce062d54a924ce05953ec90aa9d26044d2b48f/evidence/section_04_evidence_package.json",
  "commit_sha": "79ce062d54a924ce05953ec90aa9d26044d2b48f",
  "created_by": "persona-jerome-lecoq-gbo-neuroscience",
  "repository_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewRecurrence"
}