In mouse vM1, vS1, and S2, laminar maps of excitatory local circuits converge o…

{
  "n": 0,
  "doi": "10.1371/journal.pbio.1000572",
  "claim": "In mouse vM1, vS1, and S2, laminar maps of excitatory local circuits converge on a prominent descending pathway from L2/3→L5, with the L2/3→L5 connection the most conserved across areas.",
  "cite_key": "Hooks2011",
  "evidence": "Glutamate uncaging and laser-scanning photostimulation laminar mapping in mouse vM1, vS1 barrel, and S2.",
  "effect_size": "Conserved L2/3→L5; variable L4→L2/3 and L6 pathways (relative strength matrices in paper).",
  "text_access": "abstract_only",
  "study_system": "mouse vibrissal M1, S1 barrel cortex, and S2; laminar circuit mapping via glutamate uncaging in acute slices",
  "argument_role": "supporting",
  "replication_status": "independently_replicated",
  "claim_source_sentence": "In vM1, the strongest projection was L2/3→L5. In vS1, strong projections were L2/3→L5 and L4→L3. L6 input and output were weak in both areas. In S2, L2/3→L5 exceeded the strength of the ascending L4→L3 projection, and local input to L6 was prominent. The most conserved pathways were L2/3→L5, and the most variable were L4→L2/3 and pathways involving L6.",
  "source_provenance_status": "non_substring_match",
  "replication_evidence_dois": [
    "10.1016/j.neuron.2008.12.020",
    "10.7554/eLife.71103"
  ],
  "effect_size_source_sentence": null
}

[
  "paper:82e14b69-8c1b-41b8-b15b-f103a44caf3f"
]

In vM1, the strongest projection was L2/3→L5. In vS1, strong projections were L2/3→L5 and L4→L3. L6 input and output were weak in both areas. In S2, L2/3→L5 exceeded the strength of the ascending L4→L3 projection, and local input to L6 was prominent. The most conserved pathways were L2/3→L5, and the most variable were L4→L2/3 and pathways involving L6.

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    "Local review repositories are read-only inputs.",
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