Version history

{
  "scope": "PV-EGFP transgenic mouse hippocampal slices + computational model",
  "claim_text": "Fast inhibitory synapses between PV+ basket cells, combined with electrical coupling, generate synchronized gamma oscillations with high coherence across 20-110 Hz in hippocampal interneuron network models",
  "raw_fields": {
    "n": 0,
    "doi": "10.1073/pnas.192233099",
    "claim": "Fast inhibitory synapses between PV+ basket cells, combined with electrical coupling, generate synchronized gamma oscillations with high coherence across 20-110 Hz in hippocampal interneuron network models",
    "evidence": "Fast inhibitory synapses between PV+ basket cells, combined with electrical coupling, generate synchronized gamma oscillations with high coherence across 20-110 Hz in hippocampal interneuron network models",
    "effect_size": "IPSC decay time constants of 2.5, 1.2, and 1.8 ms in DG, CA3, and CA1 respectively at 33-34C",
    "text_access": "fulltext",
    "study_system": "PV-EGFP transgenic mouse hippocampal slices + computational model",
    "replication_status": "independently_replicated",
    "claim_source_sentence": "In comparison to previous interneuron network models, our model was able to generate oscillatory activity with higher coherence over a broad range of frequencies (20-110 Hz).",
    "replication_evidence_dois": [
      "10.1523/jneurosci.16-20-06402.1996"
    ],
    "effect_size_source_sentence": "Unitary inhibitory postsynaptic currents (IPSCs) showed large amplitude and fast time course with mean amplitude-weighted decay time constants of 2.5, 1.2, and 1.8 ms in the dentate gyrus, and the cornu ammonis area 3 (CA3) and 1 (CA1), respectively (33-34°C)."
  },
  "section_id": "section_10_evidence_package",
  "source_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewPV/blob/df9fc7e8d455b084152c9d713558dae0013cef21/evidence/section_10_evidence_package.json",
  "effect_size": "IPSC decay time constants of 2.5, 1.2, and 1.8 ms in DG, CA3, and CA1 respectively at 33-34C",
  "review_repo": "ComputationalReviewPV",
  "section_ref": "wiki_page:computationalreviewpv-10",
  "source_kind": "review_finding",
  "source_path": "evidence/section_10_evidence_package.json",
  "source_refs": [
    "paper:paper-a9bffd9b9fbb"
  ],
  "source_span": "In comparison to previous interneuron network models, our model was able to generate oscillatory activity with higher coherence over a broad range of frequencies (20-110 Hz).",
  "study_system": "PV-EGFP transgenic mouse hippocampal slices + computational model",
  "evidence_refs": [
    {
      "ref": "paper:paper-a9bffd9b9fbb"
    }
  ],
  "section_title": "Oscillations and Network Dynamics: Gamma, Ripples, and Synchrony",
  "source_policy": {
    "mode": "public_source_pointer_with_short_context",
    "notes": [
      "Local review repositories are read-only inputs.",
      "SciDEX stores paper metadata, structured evidence, file pointers, and short citation contexts; it does not copy full review prose."
    ],
    "source_commit_sha": "df9fc7e8d455b084152c9d713558dae0013cef21",
    "source_repository_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewPV"
  },
  "evidence_summary": "Fast inhibitory synapses between PV+ basket cells, combined with electrical coupling, generate synchronized gamma oscillations with high coherence across 20-110 Hz in hippocampal interneuron network models",
  "review_bundle_ref": "analysis_bundle:ab-e6261c8263e7",
  "replication_status": "independently_replicated",
  "review_package_ref": "analysis_bundle:ab-e6261c8263e7",
  "source_artifact_ref": "wiki_page:computationalreviewpv-10",
  "origin_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewPV/blob/df9fc7e8d455b084152c9d713558dae0013cef21/evidence/section_10_evidence_package.json",
  "commit_sha": "df9fc7e8d455b084152c9d713558dae0013cef21",
  "created_by": "persona-jerome-lecoq-gbo-neuroscience",
  "repository_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewPV"
}