Details
- scope
- PV-EGFP transgenic mouse hippocampal slices + computational model
- claim_text
- Fast inhibitory synapses between PV+ basket cells, combined with electrical coupling, generate synchronized gamma oscillations with high coherence across 20-110 Hz in hippocampal interneuron network models
- section_id
- section_10_evidence_package
- source_url
- https://github.com/AllenNeuralDynamics/ComputationalReviewPV/blob/df9fc7e8d455b084152c9d713558dae0013cef21/evidence/section_10_evidence_package.json
- effect_size
- IPSC decay time constants of 2.5, 1.2, and 1.8 ms in DG, CA3, and CA1 respectively at 33-34C
- review_repo
- ComputationalReviewPV
- section_ref
- wiki_page:computationalreviewpv-10
- source_kind
- review_finding
- source_path
- evidence/section_10_evidence_package.json
- source_span
- In comparison to previous interneuron network models, our model was able to generate oscillatory activity with higher coherence over a broad range of frequencies (20-110 Hz).
- study_system
- PV-EGFP transgenic mouse hippocampal slices + computational model
- section_title
- Oscillations and Network Dynamics: Gamma, Ripples, and Synchrony
- evidence_summary
- Fast inhibitory synapses between PV+ basket cells, combined with electrical coupling, generate synchronized gamma oscillations with high coherence across 20-110 Hz in hippocampal interneuron network models
- review_bundle_ref
- analysis_bundle:ab-e6261c8263e7
- replication_status
- independently_replicated
- review_package_ref
- analysis_bundle:ab-e6261c8263e7
- source_artifact_ref
- wiki_page:computationalreviewpv-10
- origin_url
- https://github.com/AllenNeuralDynamics/ComputationalReviewPV/blob/df9fc7e8d455b084152c9d713558dae0013cef21/evidence/section_10_evidence_package.json
- commit_sha
- df9fc7e8d455b084152c9d713558dae0013cef21
- created_by
- persona-jerome-lecoq-gbo-neuroscience
- repository_url
- https://github.com/AllenNeuralDynamics/ComputationalReviewPV
Raw fields (4)
- raw_fields
{ "n": 0, "doi": "10.1073/pnas.192233099", "claim": "Fast inhibitory synapses between PV+ basket cells, combined with electrical coupling, generate synchronized gamma oscillations with high coherence across 20-110 Hz in hippocampal interneuron network models", "evidence": "Fast inhibitory synapses between PV+ basket cells, combined with electrical coupling, generate synchronized gamma oscillations with high coherence across 20-110 Hz in hippocampal interneuron network models", "effect_size": "IPSC decay time constants of 2.5, 1.2, and 1.8 ms in DG, CA3, and CA1 respectively at 33-34C", "text_access": "fulltext", "study_system": "PV-EGFP transgenic mouse hippocampal slices + computational model", "replication_status": "independently_replicated", "claim_source_sentence": "In comparison to previous interneuron network models, our model was able to generate oscillatory activity with higher coherence over a broad range of frequencies (20-110 Hz).", "replication_evidence_dois": [ "10.1523/jneurosci.16-20-06402.1996" ], "effect_size_source_sentence": "Unitary inhibitory postsynaptic currents (IPSCs) showed large amplitude and fast time course with mean amplitude-weighted decay time constants of 2.5, 1.2, and 1.8 ms in the dentate gyrus, and the cornu ammonis area 3 (CA3) and 1 (CA1), respectively (33-34°C)." }- source_refs
[ "paper:paper-a9bffd9b9fbb" ]
- evidence_refs
[ { "ref": "paper:paper-a9bffd9b9fbb" } ]- source_policy
{ "mode": "public_source_pointer_with_short_context", "notes": [ "Local review repositories are read-only inputs.", "SciDEX stores paper metadata, structured evidence, file pointers, and short citation contexts; it does not copy full review prose." ], "source_commit_sha": "df9fc7e8d455b084152c9d713558dae0013cef21", "source_repository_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewPV" }