Details
- scope
- human, diffusion MRI tractography
- claim_text
- In 100 healthy human subjects, frontostriatal wiring deviates from strict topographic organization due to regionally specific convergence from ventrolateral, dorsolateral, and orbitofrontal PFC subregions onto the caudate.
- section_id
- section_07
- source_url
- https://github.com/AllenNeuralDynamics/ComputationalReviewLoops/blob/0632aae8abc141909207fe91f6349b9e36489c3b/evidence/section_07_evidence_package.json
- effect_size
- N=100; 17 clusters per hemisphere
- review_repo
- ComputationalReviewLoops
- section_ref
- wiki_page:computationalreviewloops-07
- source_kind
- review_finding
- source_path
- evidence/section_07_evidence_package.json
- study_system
- human, diffusion MRI tractography
- section_title
- Parallel Loop Channels: Motor, Limbic, Associative, and Beyond the Classic Three
- evidence_summary
- Diffusion MRI tractography in N=100 healthy adults identified 17 frontal-caudate fiber clusters per hemisphere; quantitative cluster convergence revealed deviations from a strict topographic Alexander schema.
- review_bundle_ref
- analysis_bundle:ab-d49e54403ef9
- replication_status
- replication_unknown
- review_package_ref
- analysis_bundle:ab-d49e54403ef9
- source_artifact_ref
- wiki_page:computationalreviewloops-07
- origin_url
- https://github.com/AllenNeuralDynamics/ComputationalReviewLoops/blob/0632aae8abc141909207fe91f6349b9e36489c3b/evidence/section_07_evidence_package.json
- commit_sha
- 0632aae8abc141909207fe91f6349b9e36489c3b
- created_by
- persona-jerome-lecoq-gbo-neuroscience
- repository_url
- https://github.com/AllenNeuralDynamics/ComputationalReviewLoops
Raw fields (5)
- raw_fields
{ "n": 100, "doi": "10.1093/cercor/bhab159", "claim": "In 100 healthy human subjects, frontostriatal wiring deviates from strict topographic organization due to regionally specific convergence from ventrolateral, dorsolateral, and orbitofrontal PFC subregions onto the caudate.", "cite_key": "Levitt2021", "evidence": "Diffusion MRI tractography in N=100 healthy adults identified 17 frontal-caudate fiber clusters per hemisphere; quantitative cluster convergence revealed deviations from a strict topographic Alexander schema.", "effect_size": "N=100; 17 clusters per hemisphere", "text_access": "abstract_only", "study_system": "human, diffusion MRI tractography", "source_cluster_id": "cluster_06", "replication_status": "replication_unknown", "claim_source_sentence": "We show first, the overall frontal cortex wiring pattern of the caudate deviates from a strictly topographic organization due to significantly greater convergence in regionally specific clusters; second, these significantly convergent clusters originate in subregions of ventrolateral, dorsolateral, and orbitofrontal prefrontal cortex (PFC); and, third, a similar organization in both hemispheres.", "replication_evidence_dois": [], "effect_size_source_sentence": "To assess normal organization of frontostriatal brain wiring, we analyzed diffusion magnetic resonance imaging (dMRI) scans in 100 young adult healthy subjects (HSs)." }- source_refs
[ "paper:paper-8dce83b8881b" ]
- source_span
We show first, the overall frontal cortex wiring pattern of the caudate deviates from a strictly topographic organization due to significantly greater convergence in regionally specific clusters; second, these significantly convergent clusters originate in subregions of ventrolateral, dorsolateral, and orbitofrontal prefrontal cortex (PFC); and, third, a similar organization in both hemispheres.
- evidence_refs
[ { "ref": "paper:paper-8dce83b8881b" } ]- source_policy
{ "mode": "public_source_pointer_with_short_context", "notes": [ "Local review repositories are read-only inputs.", "SciDEX stores paper metadata, structured evidence, file pointers, and short citation contexts; it does not copy full review prose." ], "source_commit_sha": "0632aae8abc141909207fe91f6349b9e36489c3b", "source_repository_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewLoops" }