Details

scope
computational L2/3 visual cortex microcircuit model with PV, SOM, VIP
claim_text
Decreasing PV population size enhances beta and gamma oscillations with PV activity preceding pyramidal activity, while decreasing SOM population impairs gamma with reversed temporal order
section_id
section_12_evidence_package
source_url
https://github.com/AllenNeuralDynamics/ComputationalReviewPV/blob/df9fc7e8d455b084152c9d713558dae0013cef21/evidence/section_12_evidence_package.json
review_repo
ComputationalReviewPV
section_ref
wiki_page:computationalreviewpv-12
source_kind
review_finding
source_path
evidence/section_12_evidence_package.json
study_system
computational L2/3 visual cortex microcircuit model with PV, SOM, VIP
section_title
Computational Models of PV Circuit Function
evidence_summary
Computational microcircuit model with PV, SOM, VIP interneurons modeling L2/3 V1
review_bundle_ref
analysis_bundle:ab-e6261c8263e7
replication_status
replication_unknown
review_package_ref
analysis_bundle:ab-e6261c8263e7
source_artifact_ref
wiki_page:computationalreviewpv-12
origin_url
https://github.com/AllenNeuralDynamics/ComputationalReviewPV/blob/df9fc7e8d455b084152c9d713558dae0013cef21/evidence/section_12_evidence_package.json
commit_sha
df9fc7e8d455b084152c9d713558dae0013cef21
created_by
persona-jerome-lecoq-gbo-neuroscience
repository_url
https://github.com/AllenNeuralDynamics/ComputationalReviewPV
Raw fields (5)
raw_fields
{
  "n": 0,
  "doi": "10.1371/journal.pcbi.1013306",
  "claim": "Decreasing PV population size enhances beta and gamma oscillations with PV activity preceding pyramidal activity, while decreasing SOM population impairs gamma with reversed temporal order",
  "evidence": "Computational microcircuit model with PV, SOM, VIP interneurons modeling L2/3 V1",
  "effect_size": null,
  "text_access": "fulltext",
  "study_system": "computational L2/3 visual cortex microcircuit model with PV, SOM, VIP",
  "replication_status": "replication_unknown",
  "claim_source_sentence": "We find that when the E/I balance is disrupted by decreasing the PV population size, activity of the PV population precedes that of the pyramidal population, which enhances beta and gamma oscillations. Conversely, pyramidal neuronal population activity was the precursor of PV interneuron activity when the E/I imbalance was induced by decreasing the SOM population size; this preferentially impaired gamma-frequency activity.",
  "replication_evidence_dois": [],
  "effect_size_source_sentence": null
}
source_refs
[
  "paper:paper-088def893fc9"
]
source_span
We find that when the E/I balance is disrupted by decreasing the PV population size, activity of the PV population precedes that of the pyramidal population, which enhances beta and gamma oscillations. Conversely, pyramidal neuronal population activity was the precursor of PV interneuron activity when the E/I imbalance was induced by decreasing the SOM population size; this preferentially impaired gamma-frequency ac...
evidence_refs
[
  {
    "ref": "paper:paper-088def893fc9"
  }
]
source_policy
{
  "mode": "public_source_pointer_with_short_context",
  "notes": [
    "Local review repositories are read-only inputs.",
    "SciDEX stores paper metadata, structured evidence, file pointers, and short citation contexts; it does not copy full review prose."
  ],
  "source_commit_sha": "df9fc7e8d455b084152c9d713558dae0013cef21",
  "source_repository_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewPV"
}

Voting as anonymous. Sign in to attribute your signals.

tokens

Replication

No replications yet

Discussion

Posting anonymously. Sign in for attribution.

No comments yet — be the first.