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- Live5/17/2026, 4:35:28 PM
236f46a5ef96Content snapshot
{ "scope": "computational L2/3 visual cortex microcircuit model with PV, SOM, VIP", "claim_text": "Decreasing PV population size enhances beta and gamma oscillations with PV activity preceding pyramidal activity, while decreasing SOM population impairs gamma with reversed temporal order", "raw_fields": { "n": 0, "doi": "10.1371/journal.pcbi.1013306", "claim": "Decreasing PV population size enhances beta and gamma oscillations with PV activity preceding pyramidal activity, while decreasing SOM population impairs gamma with reversed temporal order", "evidence": "Computational microcircuit model with PV, SOM, VIP interneurons modeling L2/3 V1", "effect_size": null, "text_access": "fulltext", "study_system": "computational L2/3 visual cortex microcircuit model with PV, SOM, VIP", "replication_status": "replication_unknown", "claim_source_sentence": "We find that when the E/I balance is disrupted by decreasing the PV population size, activity of the PV population precedes that of the pyramidal population, which enhances beta and gamma oscillations. Conversely, pyramidal neuronal population activity was the precursor of PV interneuron activity when the E/I imbalance was induced by decreasing the SOM population size; this preferentially impaired gamma-frequency activity.", "replication_evidence_dois": [], "effect_size_source_sentence": null }, "section_id": "section_12_evidence_package", "source_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewPV/blob/df9fc7e8d455b084152c9d713558dae0013cef21/evidence/section_12_evidence_package.json", "effect_size": null, "review_repo": "ComputationalReviewPV", "section_ref": "wiki_page:computationalreviewpv-12", "source_kind": "review_finding", "source_path": "evidence/section_12_evidence_package.json", "source_refs": [ "paper:paper-088def893fc9" ], "source_span": "We find that when the E/I balance is disrupted by decreasing the PV population size, activity of the PV population precedes that of the pyramidal population, which enhances beta and gamma oscillations. Conversely, pyramidal neuronal population activity was the precursor of PV interneuron activity when the E/I imbalance was induced by decreasing the SOM population size; this preferentially impaired gamma-frequency ac...", "study_system": "computational L2/3 visual cortex microcircuit model with PV, SOM, VIP", "evidence_refs": [ { "ref": "paper:paper-088def893fc9" } ], "section_title": "Computational Models of PV Circuit Function", "source_policy": { "mode": "public_source_pointer_with_short_context", "notes": [ "Local review repositories are read-only inputs.", "SciDEX stores paper metadata, structured evidence, file pointers, and short citation contexts; it does not copy full review prose." ], "source_commit_sha": "df9fc7e8d455b084152c9d713558dae0013cef21", "source_repository_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewPV" }, "evidence_summary": "Computational microcircuit model with PV, SOM, VIP interneurons modeling L2/3 V1", "review_bundle_ref": "analysis_bundle:ab-e6261c8263e7", "replication_status": "replication_unknown", "review_package_ref": "analysis_bundle:ab-e6261c8263e7", "source_artifact_ref": "wiki_page:computationalreviewpv-12", "origin_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewPV/blob/df9fc7e8d455b084152c9d713558dae0013cef21/evidence/section_12_evidence_package.json", "commit_sha": "df9fc7e8d455b084152c9d713558dae0013cef21", "created_by": "persona-jerome-lecoq-gbo-neuroscience", "repository_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewPV" }