Across the mouse cerebral cortex, pyramidal-neuron projection subtypes are orga…

Across the mouse cerebral cortex, pyramidal-neuron projection subtypes are organized across layers: L2/3 cells make cortico-cortical projections that integrate sensory and motor information, whereas L5 and L6 cells contribute to both inter-areal cortical projections and to subcortical projection pathways involved in behavior.

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  "doi": "10.1002/jnr.23978",
  "claim": "Across the mouse cerebral cortex, pyramidal-neuron projection subtypes are organized across layers: L2/3 cells make cortico-cortical projections that integrate sensory and motor information, whereas L5 and L6 cells contribute to both inter-areal cortical projections and to subcortical projection pathways involved in behavior.",
  "cite_key": "Gerfen2018",
  "evidence": "Review of neuroanatomical and viral targeting techniques for cortical pyramidal-neuron projection subtypes in mouse.",
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  "study_system": "mouse cerebral cortex pyramidal projection neurons (review)",
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  "claim_source_sentence": "Subtypes of cortical pyramidal neurons are organized across layers, with those in different layers distinguished by their patterns of axonal projections and connectivity. For example, those in layers 2 and 3 project between cortical areas to integrate sensory and other information with motor areas; while those in layers 5 and 6 also integrate information between cortical areas, but also project to subcortical structures involved in the generation of behavior.",
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Subtypes of cortical pyramidal neurons are organized across layers, with those in different layers distinguished by their patterns of axonal projections and connectivity. For example, those in layers 2 and 3 project between cortical areas to integrate sensory and other information with motor areas; while those in layers 5 and 6 also integrate information between cortical areas, but also project to subcortical struct...

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