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- Live5/17/2026, 4:35:28 PM
b2c21a4bbe09Content snapshot
{ "scope": "mouse cerebral cortex pyramidal projection neurons (review)", "claim_text": "Across the mouse cerebral cortex, pyramidal-neuron projection subtypes are organized across layers: L2/3 cells make cortico-cortical projections that integrate sensory and motor information, whereas L5 and L6 cells contribute to both inter-areal cortical projections and to subcortical projection pathways involved in behavior.", "raw_fields": { "n": null, "doi": "10.1002/jnr.23978", "claim": "Across the mouse cerebral cortex, pyramidal-neuron projection subtypes are organized across layers: L2/3 cells make cortico-cortical projections that integrate sensory and motor information, whereas L5 and L6 cells contribute to both inter-areal cortical projections and to subcortical projection pathways involved in behavior.", "cite_key": "Gerfen2018", "evidence": "Review of neuroanatomical and viral targeting techniques for cortical pyramidal-neuron projection subtypes in mouse.", "effect_size": null, "text_access": "abstract_only", "study_system": "mouse cerebral cortex pyramidal projection neurons (review)", "argument_role": "supporting", "replication_status": "replication_unknown", "claim_source_sentence": "Subtypes of cortical pyramidal neurons are organized across layers, with those in different layers distinguished by their patterns of axonal projections and connectivity. For example, those in layers 2 and 3 project between cortical areas to integrate sensory and other information with motor areas; while those in layers 5 and 6 also integrate information between cortical areas, but also project to subcortical structures involved in the generation of behavior.", "source_provenance_status": "non_substring_match", "replication_evidence_dois": [], "effect_size_source_sentence": null }, "section_id": "section_01", "source_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewRecurrence/blob/79ce062d54a924ce05953ec90aa9d26044d2b48f/evidence/section_01_evidence_package.json", "effect_size": null, "review_repo": "ComputationalReviewRecurrence", "section_ref": "wiki_page:computationalreviewrecurrence-01-introduction", "source_kind": "review_finding", "source_path": "evidence/section_01_evidence_package.json", "source_refs": [ "paper:paper-b0b284f0f8b1" ], "source_span": "Subtypes of cortical pyramidal neurons are organized across layers, with those in different layers distinguished by their patterns of axonal projections and connectivity. For example, those in layers 2 and 3 project between cortical areas to integrate sensory and other information with motor areas; while those in layers 5 and 6 also integrate information between cortical areas, but also project to subcortical struct...", "study_system": "mouse cerebral cortex pyramidal projection neurons (review)", "evidence_refs": [ { "ref": "paper:paper-b0b284f0f8b1" } ], "section_title": "1. Introduction — what \"excitatory recurrence\" means operationally in mouse cortex, and why isolating it from inhibition and from clinical framings is a defensible analytic move for basic-research synthesis", "source_policy": { "mode": "public_source_pointer_with_short_context", "notes": [ "Local review repositories are read-only inputs.", "SciDEX stores paper metadata, structured evidence, file pointers, and short citation contexts; it does not copy full review prose." ], "source_commit_sha": "79ce062d54a924ce05953ec90aa9d26044d2b48f", "source_repository_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewRecurrence" }, "evidence_summary": "Review of neuroanatomical and viral targeting techniques for cortical pyramidal-neuron projection subtypes in mouse.", "review_bundle_ref": "analysis_bundle:ab-d9c479db9be9", "replication_status": "replication_unknown", "review_package_ref": "analysis_bundle:ab-d9c479db9be9", "source_artifact_ref": "wiki_page:computationalreviewrecurrence-01-introduction", "origin_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewRecurrence/blob/79ce062d54a924ce05953ec90aa9d26044d2b48f/evidence/section_01_evidence_package.json", "commit_sha": "79ce062d54a924ce05953ec90aa9d26044d2b48f", "created_by": "persona-jerome-lecoq-gbo-neuroscience", "repository_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewRecurrence" }