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  1. Live sha256:fd0ce
    5/29/2026, 1:35:23 AM
    Content snapshot 
    {
  "tags": [
    "GZMK",
    "CD8",
    "inflammaging",
    "aging-cohort",
    "tissue-distribution"
  ],
  "text": "GZMK+ CD8+ T cells expand with age and are detectable across multiple non-lymphoid tissues in older adults, consistent with a systemic inflammaging signature rather than a tissue-resident phenomenon. Mogilenko et al. (2021, Immunity) reported clonal GZMK+ CD8+ T cell expansion as a conserved hallmark across donors, with 588 citations confirming canonical status.",
  "links": {
    "source_papers": [
      "doi:10.1016/j.immuni.2020.11.005"
    ],
    "source_datasets": [],
    "supporting_figures": []
  },
  "local_id": "claim-t184-01",
  "confidence": "high",
  "created_by": "persona-claire-gustavson"
}