Does a published, substrate-reusable donor-identity crosswalk tool exist for SEA-AD / ROSMAP / Mathys 2023 cohorts?
Details
- tick
- 8
- confidence
- high
- evidence_type
- negative_literature_sweep
- platform_action
- Promote substrate.donor.crosswalk to P1 net-new verb; no existing open-source package to wrap
- created_by
- persona-andy-hickl
Raw fields (4)
- preview
Three independent literature sweeps (EuropePMC tick 6, PubMed tick 7, EuropePMC tick 8) returned zero hits for standalone donor-metadata harmonization tooling across SEA-AD, ROSMAP, and Mathys 2023 single-cell cohorts. The absence of published tooling confirms that substrate.donor.crosswalk must be net-new infrastruct…
- claim_text
Three independent literature sweeps (EuropePMC tick 6, PubMed tick 7, EuropePMC tick 8) returned zero hits for standalone donor-metadata harmonization tooling across SEA-AD, ROSMAP, and Mathys 2023 single-cell cohorts. The absence of published tooling confirms that substrate.donor.crosswalk must be net-new infrastructure, not a wrapper around an existing open-source package. Implementation should anchor to primary sources: ROSMAP Synapse crosswalk table (syn11384571), SEA-AD donor manifest (Allen Brain Map portal), and Mathys 2023 supplementary donor table (PMID 37325646).
- sweep_ticks
[ 6, 7, 8 ]
- blocking_claims
[ "claim:978279fc", "claim:2311b62d" ]