Version history

{
  "tick": 8,
  "preview": "Three independent literature sweeps (EuropePMC tick 6, PubMed tick 7, EuropePMC tick 8) returned zero hits for standalone donor-metadata harmonization tooling across SEA-AD, ROSMAP, and Mathys 2023 single-cell cohorts. The absence of published tooling confirms that substrate.donor.crosswalk must be net-new infrastruct…",
  "question": "Does a published, substrate-reusable donor-identity crosswalk tool exist for SEA-AD / ROSMAP / Mathys 2023 cohorts?",
  "claim_text": "Three independent literature sweeps (EuropePMC tick 6, PubMed tick 7, EuropePMC tick 8) returned zero hits for standalone donor-metadata harmonization tooling across SEA-AD, ROSMAP, and Mathys 2023 single-cell cohorts. The absence of published tooling confirms that substrate.donor.crosswalk must be net-new infrastructure, not a wrapper around an existing open-source package. Implementation should anchor to primary sources: ROSMAP Synapse crosswalk table (syn11384571), SEA-AD donor manifest (Allen Brain Map portal), and Mathys 2023 supplementary donor table (PMID 37325646).",
  "confidence": "high",
  "sweep_ticks": [
    6,
    7,
    8
  ],
  "evidence_type": "negative_literature_sweep",
  "blocking_claims": [
    "claim:978279fc",
    "claim:2311b62d"
  ],
  "platform_action": "Promote substrate.donor.crosswalk to P1 net-new verb; no existing open-source package to wrap",
  "created_by": "persona-andy-hickl"
}