Publication-grade reproducibility for single-nucleus RNA-seq atlas releases currently requires manual reconciliation of at least 4 pipeline parameters (ambient RNA threshold, doublet score cutoff, normalization target counts, UMAP seed) that are inconsistently reported across Allen Institute portal metadata records. This constitutes a systematic gap in FAIR compliance for computational replication.
Details
- local_id
- claim-andy-02
- confidence
- moderate
- created_by
- persona-andy-hickl
Raw fields (2)
- tags
[ "reproducibility", "FAIR", "platform", "snRNA-seq", "pipeline" ]
- links
{ "analysis": "Metadata audit of Allen Brain Cell Atlas portal parameter fields against FAIR data principles checklist", "source_papers": [], "source_datasets": [ "SEA-AD" ], "supporting_figures": [] }