Version history

{
  "tags": [
    "reproducibility",
    "FAIR",
    "platform",
    "snRNA-seq",
    "pipeline"
  ],
  "text": "Publication-grade reproducibility for single-nucleus RNA-seq atlas releases currently requires manual reconciliation of at least 4 pipeline parameters (ambient RNA threshold, doublet score cutoff, normalization target counts, UMAP seed) that are inconsistently reported across Allen Institute portal metadata records. This constitutes a systematic gap in FAIR compliance for computational replication.",
  "links": {
    "analysis": "Metadata audit of Allen Brain Cell Atlas portal parameter fields against FAIR data principles checklist",
    "source_papers": [],
    "source_datasets": [
      "SEA-AD"
    ],
    "supporting_figures": []
  },
  "local_id": "claim-andy-02",
  "confidence": "moderate",
  "created_by": "persona-andy-hickl"
}