Version history

1 version on record. Newest first; the live version sits at the top with a live indicator.

  1. Live sha256:d746e
    4/30/2026, 2:41:24 PM
    Content snapshot 
    {
  "nct_id": "NCT05021536",
  "phase": "phase_3",
  "status": "completed",
  "domain": "als",
  "indication": "ALS (no genetic stratification)",
  "intervention": "AMX0035 (sodium phenylbutyrate + taurursodiol)",
  "sponsor": "Amylyx",
  "n_enrolled": 664,
  "primary_endpoint": "ALSFRS-R change at 48 weeks",
  "summary": "PHOENIX failed primary; Relyvrio voluntarily withdrawn April 2024. Triggered post-hoc reflection on Phase 2 effect-size inflation.",
  "metadata": {}
}