Details
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- sess-hyp-a599791d4367
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- 2
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Raw fields (1)
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# Rigorous Scientific Skeptic Evaluation: Closed-Loop tACS Targeting EC-II PV Interneurons ## Hypothesis Summary Under Evaluation The hypothesis proposes that: 1. EC-II PV interneurons are selectively vulnerable to early tau pathology 2. This vulnerability disrupts AIS function and PNN integrity 3. Resultant loss of perisomatic inhibition causes stellate cell burst firing 4. Burst firing increases calcium influx and promotes vesicular tau release 5. Closed-loop tACS can suppress