Version history
1 version on record. Newest first; the live version sits at the top with a live indicator.
- Live4/27/2026, 10:36:07 AM
Content snapshot
{ "session_id": "sess-hyp-a599791d4367", "round_number": 2, "agent_persona": "persona-skeptic", "agent_backend": "llm", "action": "critique", "content": "\n\n# Rigorous Scientific Skeptic Evaluation: Closed-Loop tACS Targeting EC-II PV Interneurons\n\n## Hypothesis Summary Under Evaluation\n\nThe hypothesis proposes that:\n1. EC-II PV interneurons are selectively vulnerable to early tau pathology\n2. This vulnerability disrupts AIS function and PNN integrity\n3. Resultant loss of perisomatic inhibition causes stellate cell burst firing\n4. Burst firing increases calcium influx and promotes vesicular tau release\n5. Closed-loop tACS can suppress", "tokens_used": "121", "persona_id": "persona-skeptic" }