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Wiki pages (5)
SciDEX wiki entries that cover this entity. Different pages may focus on the gene, protein, or disease aspects of the same canonical id.
- ABCA1 - ATP-Binding Cassette Transporter A1
ABCA1["ABCA1"] ds_83b31ef18d49 -->|"data in"| ABCA1 ABCA1 -->|"provides data
Read more → - ABCA1 Gene
ABCA1 Gene - ATP-Binding Cassette Transporter A1 ABCA1 — ATP-Binding
Read more → - ABCA1→Cholesterol Efflux→APOE Lipidation→Alzheimer's Disease Causal Chain
ABCA1 expression | | Gene therapy | AAV-ABCA1 | Preclinical | Direct ABCA1 delivery
Read more → - ABCA1 Protein
ABCA1 Protein ## Introduction Abca1 Protein is an important component in the neurobiology
Read more → - abca1-protein
abca1-protein ## Overview abca1-protein Symbol ABCA1 Full Name abca1
Read more →
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Related hypotheses
- HDL/apoE Particle Remodeling as a Therapeutic Switch for CAA Prevention
Prevention starts from the claim that modulating ABCA1 within the disease context of neurodegeneration ... mechanisms. The ATP-binding cassette transporter A1 (ABCA1) serves as th…
- miR-33 Antisense Oligonucleotide Hyper-Lipidation Strategy
protein's ability to acquire lipids from ABCA1-mediated efflux. MicroRNA-33 (miR-33) emerges ... process through its post-transcriptional suppression of ABCA1, the primary cholest…
- APOE4 astrocytes exhibit impaired cholesterol efflux via ABCA1/ABCG1 transporters, driving intracellular lipid droplet accumulation and secondary neuronal cholesterol deficiency
deficiency starts from the claim that modulating ABCA1, ABCG1 within the disease context of neuroscience ... action of ATP-binding cassette (ABC) transporters ABCA1 and ABCG1, whi…
- C1q-Mediated Delivery of miR-33 Antisense Oligonucleotides for Enhanced APOE4 Lipidation
cells, the primary brain cell type expressing ABCA1. Once delivered, the miR-33 ASOs would ... aggressively upregulate ABCA1 expression by removing post-transcriptional suppressio…
- APOE4-Specific Microglial Metabolic Rescue
starts from the claim that modulating APOE, ABCA1, LDLR within the disease context of neurodegeneration ... starts from the claim that modulating APOE, ABCA1, LDLR within the dise…