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Wiki pages (5)
SciDEX wiki entries that cover this entity. Different pages may focus on the gene, protein, or disease aspects of the same canonical id.
- AhR Modulator Therapy for Neurodegenerative Diseases
AhR Modulator Therapy for Neurodegenerative Diseases ## Overview AhR Modulator Therapy
Read more → - Neprilysin (NEP / CD10 / MME)
AHR["AHR"] AHR -->|"activates"| NEPRILYSIN ALZHEIMER -->|"activates"| NEPRILYSIN APP -->|"activates
Read more → - IDO1 — Indoleamine 2,3-Dioxygenase 1
AhR)**: Kynurenine itself activates AhR, which further upregulates IDO1 (positive
Read more → - ARNT - Aryl Hydrocarbon Receptor Nuclear Translocator
AHR["AHR"] -->|"interacts with"| ARNT["ARNT"] CLOCK["CLOCK"] -->|"expressed in"| ARNT
Read more → - XPA Gene
AHR["AHR"] XPA["XPA"] -->|"regulates"| MTOR["MTOR"] XPA["XPA"] -->|"regulates
Read more →
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Related hypotheses
- Aryl Hydrocarbon Receptor (AhR) Activation by Microbiome Metabolites Promotes A2 Polarization
Mechanistic Overview Aryl Hydrocarbon Receptor (AhR) Activation by Microbiome Metabolites Promotes A2 Polarization starts from ... claim that modulating AHR, CYP1A1, NFKB1, IL6 wi…
- Aryl Hydrocarbon Receptor (AHR) Activation in B Cells Determines AQP4 Tolerance Fate
Mechanism and Rationale** The aryl hydrocarbon receptor (AHR) represents a ligand-activated transcription factor belonging ... disorder (NMOSD), the proposed mechanism centers on…
- Gut Bacterial Metabolite-AhR Dysregulation Converts SCFA-Deficiency into IDO1-Driven Kynurenine Neurotoxicity
Aryl hydrocarbon receptor (AhR), expressed in microglia, astrocytes, and neurons, normally ligates tryptophan catabolites from ... propionate). Dysbiosis depletes tryptophan-metab…