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Wiki pages (5)
SciDEX wiki entries that cover this entity. Different pages may focus on the gene, protein, or disease aspects of the same canonical id.
- Syntenin-1 Exosome Biogenesis Modulation Therapy for Neurodegeneration
ALIX - **ALIX inhibitors** — Prevent Syntenin-ALIX complex formation - **Peptide blockers
Read more → - Exosome Biogenesis in Neurodegeneration
ALIX**: Bridges syntenin to ESCRT machinery The syndecan-syntenin-ALIX
Read more → - Validated Hypothesis: Extracellular Vesicle Biogenesis Modulation
ALIX- and ESCRT-III-dependent sorting of tetraspanins to exosomes
Read more → - Extracellular Vesicle-Mediated Synuclein Propagation Hypothesis in Parkinson's Disease
ALIX** | ESCRT accessory, EV biogenesis | Multivesicular body | [ALIX](/genes/alix) | | **VPS4
Read more → - Extracellular Vesicles in Neurodegeneration
Alix, TSG101 - **Heat shock proteins**: Hsp70, Hsp90 - **Membrane proteins**: Integrins
Read more →
Graph neighborhood (6 nodes · 6 edges)
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Related hypotheses
- Blocking Tau Packaging into Small Extracellular Vesicles via ESCRT-III Pathway
starts from the claim that modulating PDGRIP1L (ALIX) within the disease context of neuroscience ... starts from the claim that modulating PDGRIP1L (ALIX) within the disease conte…
- Rab27A/B-mediated exosomal tau secretion from microglia drives frontal cortex propagation at Braak III-VI
recipient cells. [PMID:33509923]. 4. Syntenin-ALIX pathway preferentially packages phosphorylated tau into exosomes. [PMID ... recipient cells. [PMID:33509923]. 4. Syntenin-ALIX p…
- Extracellular Vesicle Biogenesis Modulation
states. ## Evidence Supporting the Hypothesis 1. ALIX- and ESCRT-III-dependent sorting of tetraspanins ... Classical swine fever virus recruits ALIX and ESCRT-III to facilitate v…
- Lysosomal Membrane Repair Enhancement
autoinhibitory region undergoes conformational changes upon activation. ALIX (ALG-2 Interacting Protein X) serves ... have identified compound series targeting the CHMP2B-ALIX int…
- Gamma-Entrained P-tau217 Biomarker Cascades Optimize lncRNA-9969 Exosome Therapy Precision in Early AD
exosome delivery mechanism, **CD63**, **CD9**, and **ALIX** (PDCD6IP) serve as canonical exosome surface markers whose ... exosome delivery mechanism, **CD63**, **CD9**, and **ALI…