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Wiki pages (5)
SciDEX wiki entries that cover this entity. Different pages may focus on the gene, protein, or disease aspects of the same canonical id.
- ATG5 — Autophagy Related 5
ATG5 ATG5 -->|"participates_in"| AUTOPHAGY ATG5 -->|"regulates"| EIF4EBP1 ATG5 -->|"inhibits
Read more → - ATG5 Protein
ATG5["ATG5"] AUTOPHAGY["AUTOPHAGY"] -.->|"inhibits"| ATG5["ATG5"] APOPTOSIS["APOPTOSIS"] -->|"activates
Read more → - ATG5 — ATG5 Protein
ATG5 — ATG5 Protein ## Introduction Atg5 — Atg5 Protein is an important
Read more → - ATG12 — Autophagy Related 12
ATG5["ATG5"] ATG5 -->|"activates"| ATG12 AUTOPHAGY -->|"activates"| ATG12 AUTOPHAGY -->|"interacts
Read more → - macroautophagy-dysfunction-parkinsons
ATG5** | Autophagosome formation | ATG5 mutations cause early-onset PD | | **ATG7
Read more →
Graph neighborhood (30 nodes · 232 edges)
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Related hypotheses
- Transcriptional Autophagy-Lysosome Coupling
autophagy: - Upregulates >50 autophagy genes including ATG5, ATG7, ATG12, LC3B, BECN1, SQSTM1/p62, ULK1 - Increases autophagosome ... Formation (FOXO1)** - ULK1 kinase initiates p…
- Circadian Clock-Autophagy Synchronization
genome, including key autophagy regulators such as ATG5, ATG7, LC3B, and BECN1. The molecular synchronization ... deacetylates and activates key autophagy proteins including ATG5,…
- Circadian-Synchronized Proteostasis Enhancement
autophagy-related genes including *ULK1*, *ATG7*, *ATG5*, *BECN1* (Beclin 1), and *MAP1LC3B* (microtubule-associated protein ... greater upregulation of additional autophagy genes…
- Senescent Cell Mitochondrial DNA Release
cells, reduced expression of autophagy-related proteins (ATG5, ATG7, LC3B) and impaired lysosomal function result ... DNASE2** expression correlates positively with autophagy mark…
- Autophagy-Epigenetic Feedback Loop Creates a Compounding Biomarker Signal — Autophagy Flux Methylation as an AD Stage Chronometer
dysfunctional mitochondria. Autophagy regulatory genes (BECN1, ATG5, ATG7, TFEB) contain CpG-rich promoters subject