No definition recorded for this entity.
Wiki pages (5)
SciDEX wiki entries that cover this entity. Different pages may focus on the gene, protein, or disease aspects of the same canonical id.
- NUP214 — Nucleoporin 214
CRM1-cargo-RanGTP complex traverses the NPC central channel through
Read more → - Nuclear Pore Complex Dysfunction in Neurodegeneration
CRM1), and NXF1/TAP bind to cargo proteins and interact with
Read more → - XPO1/CRM1 Protein
CRM1) Gene XPO1 UniProt ID O14980 Molecular Weight 124 kDa Length
Read more → - Nucleocytoplasmic Transport Defects in Neurodegenerative Diseases
CRM1 - Regulated by phosphorylation **Other NES types:** - Proline-rich NES - Arginine
Read more → - HDAC5 Protein
CRM1-dependent nuclear export signal **Catalytic Domain (aa 482-680):** - Zinc
Read more →
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Related hypotheses
- Nuclear Export Deficits Increase Cytosolic TDP-43 Burden
rich NES (amino acids 239-250) facilitates CRM1-dependent export. Under normal conditions ... effect where both direct nuclear export (via CRM1) and coupled transcription-export (…
- Nuclear Pore and Nucleocytoplasmic Transport Machinery as Gatekeepers
following mechanistic claim: Export factors (NXF1, CRM1, importins) and nuclear pore components are recruited