Chi3l1/YKL-40

Wiki pages (4)

SciDEX wiki entries that cover this entity. Different pages may focus on the gene, protein, or disease aspects of the same canonical id.

• Validated Hypothesis: miR-155/Interferon-gamma Feedback Loop as a Reversible Molecular Switch for Protective Microglial State Transition

  CHI3L1/YKL-40). Cognitive assessments must differentiate between domain-specific improvements that

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• Validated Hypothesis: Beta-Hydroxybutyrate Receptor (HCAR2) Signaling Links Ketone Deficiency to Neuroinflammation

  CHI3L1/YKL-40) and glial fibrillary acidic protein (GFAP), established indicators of glial

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• CHI3L1 Gene

  CHI3L1/YKL-40 shows cell-type and region-specific expression: - [*Brain cells

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• AAN 2026 — Multiple Sclerosis

  CHI3L1/YKL-40):** Astrocyte activation marker - **OCT (optic coherence tomography):** Retinal nerve

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Graph neighborhood (4 nodes · 4 edges)

Related hypotheses

• CSF YKL-40 as a Priming-Specific Chitinase Marker

  Marker starts from the claim that modulating CHI3L1/YKL-40 within the disease context of biomarkers ... Marker starts from the claim that modulating CHI3L1/YKL-40 within the disea…

• Integrated Biomarker Panel for Therapeutic Window Identification

  states. ## Evidence Supporting the Hypothesis 1. CHI3L1/YKL-40 signaling inhibits neurogenesis in AD models. Identifier

• miR-155/Interferon-gamma Feedback Loop as a Reversible Molecular Switch for Protective Microglial State Transition

  sTREM2) and chitinase-3-like protein 1 (CHI3L1/YKL-40). Cognitive assessments must differentiate between domain-specific

• Beta-Hydroxybutyrate Receptor (HCAR2) Signaling Links Ketone Deficiency to Neuroinflammation

  decreases in chitinase-3-like protein 1 (CHI3L1/YKL-40) and glial fibrillary acidic protein (GFAP), established

• Microbiota-Microglia Axis Modulation

  concentrations of chitinase-3-like protein 1 (CHI3L1/YKL-40), a established marker of microglial activation that