No definition recorded for this entity.
Wiki pages (5)
SciDEX wiki entries that cover this entity. Different pages may focus on the gene, protein, or disease aspects of the same canonical id.
- PTK2 Protein - FAK
FAK signaling - [Aβ](/proteins/amyloid-beta) oligomers alter FAK autophosphorylation - Reduced FAK
Read more → - Focal Adhesion Kinase (FAK) Signaling Pathway
FAK phosphorylation - FAK interacts with NMDA receptor subunits - FAK regulates
Read more → - Focal Adhesion Kinase (FAK) Inhibition Therapy for Neurodegeneration
FAK activator - Microglial Phagocytosis — FAK-regulated process - Synapse Elimination — FAK
Read more → - PTK2 Gene - Focal Adhesion Kinase
FAK signaling in neurons - **[Tau](/proteins/tau) pathology**: FAK interacts with
Read more → - Integrin Signaling and Extracellular Matrix in CBS/PSP
FAK) in Tauopathies ### FAK Structure and Function Focal adhesion kinase
Read more →
Graph neighborhood (14 nodes · 16 edges)
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Related hypotheses
- αvβ3 Integrin-FAK-SYK-CARD9/NF-κB Pathway
Molecular Mechanism and Rationale** The αvβ3 integrin-FAK-SYK-CARD9/NF-κB pathway represents ... focal adhesion kinase (FAK/PTK2) recruitment and activation. FAK undergoes autop…
- TREM2 Crosstalk and Synergistic Activation of Phagocytic Transcriptome
variants. SPP1 binding to these receptors activates FAK (focal adhesion kinase) and SRC family kinases
- Metabolic Rewiring via SPP1-Induced HIF1α Glycolytic Shift
initiate a cascade through focal adhesion kinase (FAK) and subsequent activation of the PI3K/AKT signaling
- Netrin-1 Gradient Restoration
responses through activation of focal adhesion kinase (FAK) and subsequent phosphoinositide 3-kinase (PI3K)/AKT
- Profilin-1 Cytoskeletal Checkpoint Enhancement
through integrin-mediated focal adhesion complexes involving FAK (PTK2) and paxillin (PXN). Age-related decline