No definition recorded for this entity.
Wiki pages (5)
SciDEX wiki entries that cover this entity. Different pages may focus on the gene, protein, or disease aspects of the same canonical id.
- HCN1 Gene
HCN1 HCN1 -->|"associated_with"| AbsenceSeizures HCN1 -->|"associated_with"| Epileptogenesis HCN1
Read more → - HCN1 Neurons
HCN1 Neurons ## Introduction HCN1 Neurons **Category** Ion Channel-Expressing Neurons
Read more → - hcn1-protein
hcn1-protein ## Overview HCN1 (Hyperpolarization-activated Cyclic Nucleotide-gated channel
Read more → - HCN1 Protein
HCN1 Protein ## Overview HCN1 (Hyperpolarization-Activated Cyclic Nucleotide-Gated channel
Read more → - HCN and Kv Channel Modulators in Neurodegenerative Disease
HCN1-4 Forskolin HCN (via AC) 8-Br-cAMP HCN1
Read more →
Graph neighborhood (30 nodes · 64 edges)
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Related hypotheses
- HCN1-Mediated Resonance Frequency Stabilization Therapy
Mechanistic Overview HCN1-Mediated Resonance Frequency Stabilization Therapy starts from the claim that modulating HCN1 ... hyperpolarization-activated cyclic nucleotide-gated cha…
- HCN1-Selective Blockade Normalizes Thalamic Rebound Bursting in P/Q Channel Deficiency
Mechanistic Overview HCN1-Selective Blockade Normalizes Thalamic Rebound Bursting in P/Q Channel Deficiency starts from ... claim that modulating HCN1 within the disease context o…
- Closed-loop tACS targeting EC-II somatostatin interneurons to restore dendritic integration and prevent tau-mediated HCN channel dysfunction in AD
hyperphosphorylated tau directly binds to and disrupts HCN1 channel trafficking and membrane insertion ... density and compromised dendritic excitability. This tau-HCN1 interactio…
Related debates
- Is HCN1 dysfunction causal or protective in EC layer II neurodegeneration?
debate revealed conflicting evidence about whether HCN1 downregulation drives neuronal death or represents a protective ... causality question is critical for determining whether …