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Wiki pages (5)
SciDEX wiki entries that cover this entity. Different pages may focus on the gene, protein, or disease aspects of the same canonical id.
- nfat-pathway-modulators-neurodegeneration
nfat_pathway_modulators_neurod["nfat-pathway-modulators-neurodegeneration"] nfat_pathway
Read more → - NFAT2 Protein
NFAT Response Element (NFAT-RE)**: DNA sequence 5'-GGGAA(A/T)-3' bound
Read more → - NFAT3 Gene
NFAT signaling in neurons and glia. - **NFAT hyperactivation**: Chronic NFAT
Read more → - NFATc1 — Nuclear Factor of Activated T Cells 1
NFAT dynamics - Immunohistochemistry for NFAT localization ## See Also - [NFAT Signaling
Read more → - NFAT Pathway Modulator Therapy for Neurodegeneration
NFAT decoy ODN All NFAT VIVIT peptide NFAT calcineurin binding
Read more →
Graph neighborhood (24 nodes · 26 edges)
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Related hypotheses
- P2X7/P2Y12 Purinergic Signaling Connects Aβ Aggregation to SPP1 Transcription via Calcineurin/NFAT Pathway
cells. Calcineurin activation: 1. Dephosphorylates NFAT (Nuclear Factor of Activated T cells) family transcription factors ... Dephosphorylated NFAT translocates to the nucleus 3.…
- Calmodulin isoform switching from CaMK to calcineurin activation upon lysosomal permeabilization
Lysosomal calcium release specifically activates calcineurin-NFAT over CaMK pathways. [PMID:28481357]. 3. Calmodulin availability ... Lysosomal calcium release specifically activa…
- Cell-Type Specific TREM2 Upregulation in DAM Microglia
activates"| PLCG["PLCgamma"] PLCG -->|"calcium flux"| NFAT["NFAT"] NFAT -->|"transcription"| GENES["DAM Gene Program
- PIKFYVE Inhibition Activates Aggregate Exocytosis via PI(3,5)P2→TRPML1→Calcineurin→TFEB Cascade in ALS Motor Neurons
impairment in AD 3. Calcineurin dephosphorylates NFAT, promoting nuclear translocation and inflammatory gene expression ... impairment in AD 3. Calcineurin dephosphorylates NFAT, …
- Hypothesis 7: SST-SST1R/Gamma Entrainment-Enhanced Astrocyte Secretome
nuclear factor of activated T-cells (NFAT). These transcription factors translocate to the nucleus ... through CRE elements in its promoter, while NFAT regulates GPNMB expression.…