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Wiki pages (5)
SciDEX wiki entries that cover this entity. Different pages may focus on the gene, protein, or disease aspects of the same canonical id.
- nfkb-neurodegeneration
Nfkb["Nfkb"] ==>|"upregulates"| SQSTM1["SQSTM1"] Nfkb["Nfkb"] ==>|"activates"| Inflammatory_Cytokine
Read more → - NF-kB Pathway Inhibition Therapy for Neurodegeneration
nfkb_p_0["Mechanism of Action"] ideas_payload_nfkb_pathway
Read more → - NF-κB p105 Protein
NFKB TGM2 -->|"activates"| NFKB BRSK2 -->|"activates"| NFKB TMAO -->|"activates"| NFKB
Read more → - NFKBIA Gene (NFKB Inhibitor Alpha)
NFKB Inhibitor Alpha) ## Overview **NFKBIA** (NFKB Inhibitor Alpha) encodes the IκBα
Read more → - DNMT1 Gene
NFKB["NFKB"] NFKB -->|"associated with"| DNMT1 RB1["RB1"] RB1 -->|"regulates
Read more →
Graph neighborhood (30 nodes · 87 edges)
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Related hypotheses
- GATA4 Stabilization and NF-κB Co-activation Identifies Senescent Microglia
from the claim that modulating GATA4, SQSTM1/p62, NFKB subunits within the disease context of neurodegeneration ... from the claim that modulating GATA4, SQSTM1/p62, NFKB subunits…
- Apoptosis-Senescence Decision Point Intervention
Alzheimer's Disease affects WNT, p53, and NFkB Signaling determined by snRNA-seq. [PMID ... Alzheimer's Disease affects WNT, p53, and NFkB Signaling determined by snRNA-seq. [PMID
- Selective TLR4 Modulation to Prevent Gut-Derived Neuroinflammatory Priming
TRIF Pathway (delayed: IRF3, IFN-beta)"] MYD88 --> NFKB["NF-kappaB -> TNF-alpha, IL-1beta ... NFKB --> PRIMING["Microglial Priming (H3K4me1 latent enhancers)"] PRIMING --> HYPER["…
- Inhibitory Neuron-Selective WNT Signaling Restoration
Disease specifically affects WNT, p53, and NFkB signaling with cell-type specific patterns determined ... Disease specifically affects WNT, p53, and NFkB signaling with cell-type …
- SASP Modulation Rather Than Cell Elimination
Supports the hypothesis through SASP modulation NFkB senescence-related findings. Identifier https://doi.org/10.14336/ad.2023.0907. ## Contradictory