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Wiki pages (5)
SciDEX wiki entries that cover this entity. Different pages may focus on the gene, protein, or disease aspects of the same canonical id.
- SOD1 — Superoxide Dismutase 1
SOD1["SOD1"] SOD1["SOD1"] -->|"associated with"| AD["AD"] SOD1["SOD1
Read more → - SOD1 Protein
SOD1["SOD1"] ALS["ALS"] -->|"associated with"| SOD1["SOD1"] PARKINSON_S_DISEASE
Read more → - SOD1 Superoxide Dismutase 1 ALS Causal Chain
SOD1 Superoxide Dismutase 1 ALS Causal Chain ## Overview [SOD1](/genes/sod1
Read more → - SOD1 Mutations in Amyotrophic Lateral Sclerosis
SOD1 Mutations in Amyotrophic Lateral Sclerosis ## Overview Mutations in the SOD1
Read more → - SOD1 Protein (Superoxide Dismutase 1)
SOD1["SOD1"] ALS["ALS"] -->|"associated with"| SOD1["SOD1"] PARKINSON_S_DISEASE
Read more →
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Related hypotheses
- Acid-Degradable LNP-Mediated Prenatal CRISPR Intervention for Severe Neurodevelopmental Forms
neurodegeneration caused by dominant mutations in SOD1, HTT, and TARDBP genes. These three genes encode ... disease, and frontotemporal dementia with ALS, respectively. SOD1 muta…
- Multiplexed Base Editing for Simultaneous Neuroprotective Gene Activation
Activation starts from the claim that modulating SOD1, TARDBP, BDNF, GDNF, IGF-1 within ... hypothesis." Framed more explicitly, the hypothesis centers SOD1, TARDBP, BDNF, GDNF, I…
- NRF2-KEAP1 Pathway Activation to Coordinate Multi-Layer Antioxidant Defense
models and validates therapeutic targeting. In the SOD1-G93A transgenic mouse model, a gold standard ... days and reduced survival compared to SOD1-G93A mice with intact NRF2. Con…
- Metabolic Coupling Disruption Sensitizes Motor Neuron mPTP Threshold
animal models and in vitro systems. In SOD1-G93A transgenic mice, the gold standard ... show accelerated motor dysfunction when expressing mutant SOD1, with 28% reduced survival c…