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Wiki pages (5)
SciDEX wiki entries that cover this entity. Different pages may focus on the gene, protein, or disease aspects of the same canonical id.
- STING Gene
STING["STING"] STING["STING"] -->|"activates"| type_I_interferon["type I interferon
Read more → - cGAS-STING Pathway Dysregulation Hypothesis in Parkinson's Disease
STING in Peripheral Blood Mononuclear Cells Phosphorylated STING (p-STING
Read more → - cGAS-STING Signaling in Parkinson's Disease
STING Signaling in Parkinson's Disease The cGAS-STING signaling
Read more → - cGAS-STING Pathway in Neurodegeneration
STING_Signaling["STING Signaling"] C1["cGAMP binds STING"] C2["STING
Read more → - DNA Sensing Pathways in Neurodegeneration
STING_Pathway B --> P["STING Activation"] P --> Q["TBK1 Phosphorylation
Read more →
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Related hypotheses
- Mitochondrial NAD+ Salvage Enhancement
disease-relevant process. The original description reads: "STING-NAD+ Circuit Modulation for Neuroprotection ## Overview ... aging brain is the activation of STING (Stimulator of …
- STING Antagonism Prevents Acute-to-Chronic Neuroinflammation Transition via Interruption of IFN-I Feedback Looping
Mechanistic Overview STING Antagonism Prevents Acute-to-Chronic Neuroinflammation Transition via Interruption ... starts from the claim that modulating TMEM173 (STING) within the …
- cGAS-STING Senescence Circuit Disruption
synthase (cGAS) and stimulator of interferon genes (STING) pathway represents a fundamental innate immune sensing ... interferon responses to encompass multiple inflammatory pathw…
- STING Antagonists as ALS Therapeutics: Drug Repurposing
Molecular Mechanism and Rationale** The cGAS-STING (Cyclic GMP-AMP Synthase - Stimulator of Interferon Genes ... This second messenger molecule then binds to STING (TMEM173), a 3…
- Temporal cGAS-STING Activation Stage-Specific Therapeutic Targeting
Mechanistic Overview Temporal cGAS-STING Activation Stage-Specific Therapeutic Targeting starts from the claim that ... modulating STING (TMEM173) within the disease context of ne…