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Wiki pages (5)
SciDEX wiki entries that cover this entity. Different pages may focus on the gene, protein, or disease aspects of the same canonical id.
- Tumor Necrosis Factor Alpha (TNF-α) as a Neurodegenerative Disease Biomarker
tnf_trem22024] ## Therapeutic Implications ### Anti-TNF Therapies Given TNF-α's central
Read more → - TNF Signaling Pathway in Neurodegeneration
Tnf_Signaling["Tnf Signaling"] TNF["TNF"] -->|"implicated in"| Tnf_Signaling
Read more → - TNF - Tumor Necrosis Factor
TNF["TNF"] TNF["TNF"] -->|"activates"| ACOD1["ACOD1"] TNF["TNF"] -->|"causes
Read more → - TNF Gene
TNF ### Approved TNF Inhibitors Several TNF-blocking agents are approved
Read more → - xpro1595-tnf-alpha-inhibitor-alzheimers
tnf_alpha_inhibitor_a["xpro1595-tnf-alpha-inhibitor-alzheimers"] -->|"references
Read more →
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Related hypotheses
- TNF-α–C1r/C1s Bridge Between NF-κB and Classical Complement Cascade
Molecular Mechanism and Rationale** The TNF-α–C1r/C1s bridge represents a critical mechanistic link connecting ... this pathway initiates when sevoflurane exposure triggers TNF-α…
- Astrocyte-Microglia Communication Rebalancing via Cytokine Modulation
starts from the claim that modulating IL1A, TNF, C1Q within the disease context of neurodegeneration ... starts from the claim that modulating IL1A, TNF, C1Q within the disease co…
- TNF-α/IL-1β-Cx43 Hemichannel Axis as Upstream Link Between SASP and Synaptic Pruning
Mechanistic Overview TNF-α/IL-1β-Cx43 Hemichannel Axis as Upstream Link Between SASP ... Pruning starts from the claim that modulating TNF, IL1B → GJA1 → C1Q/C3 within the disease…
- Cardiovascular-Neuroinflammation Crosstalk Interruption
beta (IL-1β), tumor necrosis factor-alpha (TNF-α), and nucleotide-binding oligomerization domain ... pathology and inflammasome engagement in neurodegenerative contexts. TNF-α an…
- Selectively Inhibit Maladaptive AQP4-Driven Astrocyte-Microglia Inflammatory Signaling in Parkinsonian Injury
claim that modulating AQP4, NFKB1, IL1B, TNF within the disease context of neurodegeneration can redirect ... claim that modulating AQP4, NFKB1, IL1B, TNF within the disease conte…