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Wiki pages (5)
SciDEX wiki entries that cover this entity. Different pages may focus on the gene, protein, or disease aspects of the same canonical id.
- Exosomal miR-155 in Neurodegeneration
miR-155 | Elevated | Low | Early detection | | miR-155/let-7a ratio
Read more → - Validated Hypothesis: miR-155/Interferon-gamma Feedback Loop as a Reversible Molecular Switch for Protective Microglial State Transition
miR-155, or synthetic miR-155 mimics to enhance protective
Read more → - Non-coding RNAs in Neurodegeneration
miR-155, miR-146a**: Shared neuroinflammatory signatures across AD, PD, ALS, and MS - **miR
Read more → - MicroRNA (miRNA) Biomarkers in Neurodegenerative Disease
miR-155, miR-146a upregulated in activated microglia via NF-κB pathway
Read more → - Validated Hypothesis: Optimized Temporal Window for Metabolic Boosting Therapy Determines Success of Microglial State Transition Restoration
miR-155/IFNγ regulatory axis serves as a critical
Read more →
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Related hypotheses
- Age-Accelerated miR-155 Upregulation Primes Nigral Microglia for Parkinson's Disease Pathology
Mechanistic Overview Age-Accelerated miR-155 Upregulation Primes Nigral Microglia for Parkinson's Disease Pathology ... starts from the claim that modulating miR-155 within the di…
- miR-155/Interferon-gamma Feedback Loop as a Reversible Molecular Switch for Protective Microglial State Transition
Mechanistic Overview miR-155/Interferon-gamma Feedback Loop as a Reversible Molecular Switch for Protective Microglial ... reads: "**Molecular Mechanism and Rationale** The miR-15…
- CX3CR1-Targeted AntimiR-155 Oligonucleotides for Microglial Priming Reversal
methyl modifications blocking miR-155. Restores SOCS1 and SHIP1 translation, rebalancing H3K27ac/H3K9me3 at synaptic plasticity ... states. ## Evidence Supporting the Hypothesis 1…
- Optimized Temporal Window for Metabolic Boosting Therapy Determines Success of Microglial State Transition Restoration
microglial bioenergetics and inflammatory responses. The miR-155/IFNγ regulatory axis serves ... critical molecular switch, where IFNγ-induced miR-155 expression creates a positiv…
- TREM2-Mediated Astrocyte-Microglia Crosstalk in Neurodegeneration
conditions revealed 8-fold enrichment of miR-155 and 5-fold reduction in protective miR