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Wiki pages (5)
SciDEX wiki entries that cover this entity. Different pages may focus on the gene, protein, or disease aspects of the same canonical id.
- blood-brain-barrier
tight junction proteins to the actin cytoskeleton - Tight junction integrity
Read more → - CING1 Gene
Tight Junction Functions At epithelial and endothelial tight junctions, cingulin
Read more → - Blood-Brain Barrier Breakdown in Neurodegeneration
Tight Junction Stabilizers New approaches to stabilize tight junctions: - **ATL-313** (PEGylated
Read more → - Neurovascular Unit Dysfunction Hypothesis in Parkinson's Disease
tight junction proteins (claudin-5, occludin, ZO-1) in PD brains
Read more → - Blood-Brain Barrier
Tight Junction Complex The endothelial tight junctions represent the anatomical
Read more →
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Related hypotheses
- LRP1-Autophagy BBB Permeabilization for Antibody Transport
LRP1; ATG7; OPTN (autophagy pathway); CLDN5 (tight junctions) within the disease context of neurodegeneration ... LRP1; ATG7; OPTN (autophagy pathway); CLDN5 (tight junctions) wit…
- Focused Ultrasound with Microbubble Contrast Agents for Antibody CNS Delivery
from the claim that modulating CLDN5/ZO-1 tight junction complex; KDR/VEGFR2 within the disease context ... from the claim that modulating CLDN5/ZO-1 tight junction complex; KDR/V…
- Piezoelectric Nanochannel BBB Disruption
obstacles in treating neurodegenerative diseases, with tight junctions formed by specialized proteins creating an impermeable ... piezoelectric nanochannel system targets two crit…
- Intestinal Permeability Defects → Systemic LPS Translocation → Microglial Priming
starts from the claim that modulating Tight junction complex (CLDN1, OCLN, TJP1), LBP, CD14, TLR4 ... starts from the claim that modulating Tight junction complex (CLDN1, OCLN, TJ…
- C1q-Alectinib Complexation Disrupts Tight Junction Integrity to Enable Paracellular Brain Penetration
Mechanistic Overview C1q-Alectinib Complexation Disrupts Tight Junction Integrity to Enable Paracellular Brain Penetration starts ... Mechanistic Overview C1q-Alectinib Complexati…
Related debates
- Blood-brain barrier tight junction disruption by neuroinflammatory cytokines
blood-brain barrier (BBB) integrity through tight junction protein degradation. Key mechanisms to investigate ... MMPs (matrix metalloproteinases) that cleave tight junction prot…