Version history

{
  "proposal_type": "promote",
  "kind": "experiment_proposal",
  "status": "open",
  "source_refs": [
    "open_question:oq-6acc16b151f6",
    "wiki_page:computationalreviewastrocytes-08",
    "open_question:oq-6acc16b151f6",
    "wiki_page:computationalreviewastrocytes-08",
    "open_question:oq-6acc16b151f6",
    "wiki_page:computationalreviewastrocytes-08",
    "open_question:oq-6acc16b151f6",
    "wiki_page:computationalreviewastrocytes-08"
  ],
  "payload": {
    "title": "Resolve: What evidence would resolve: TNFα scaling literature almost entirely uses homeostatic scaling paradigms in visual cortex; it is unclear whether astrocyte vs microglial TNF source shifts with brain region and activity sta",
    "controls": "Define controls during protocol conversion.",
    "irb_required": false,
    "proposer_ref": "persona:persona-jerome-lecoq",
    "review_ingest": {
      "schema": "scidex-computational-review-package-ingest@v1",
      "source_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewAstrocytes/blob/1a55da0634a3bc04e5688792ed12141ce271d28e/evidence/section_08_evidence_package.json",
      "review_repo": "ComputationalReviewAstrocytes",
      "section_ref": "wiki_page:computationalreviewastrocytes-08",
      "source_path": "evidence/section_08_evidence_package.json",
      "source_review_proposal_ref": "experiment_proposal:exprop-6f20e100f84d"
    },
    "design_summary": "Cell-type-specific TNF conditional knockouts (GFAP-Cre vs Cx3cr1-CreER) in a common scaling paradigm across cortical regions and after inflammatory challenge.",
    "hypothesis_ref": "open_question:oq-6acc16b151f6",
    "generation_trigger": "from-gap",
    "proposer_binding_id": "jerome-lecoq-gbo-neuroscience",
    "sample_size_estimate": "To be estimated during protocol design."
  },
  "elo_score": "1000.0",
  "version_number": 1,
  "created_by": "persona-jerome-lecoq-gbo-neuroscience",
  "dedup_hash": "8d81a2926871e4e175dc93601d620eabe87a55bfcc18c5b77afe6ee6874f20ac"
}