Description
The debate highlighted that early grid cell disruption could arise from either altered neuronal resonance frequencies or upstream network changes. This distinction determines whether single-cell or circuit-level interventions are needed for functional rescue.
Source: Debate session sess_SDA-2026-04-01-gap-004 (Analysis: SDA-2026-04-01-gap-004)
Evidence summary
Resolved by hypothesis h-var-e2b5a7e7db: GluN2B-Mediated Thalamocortical Control of Glymphatic Tau Clearance. Score: 0.964. Supporting PMIDs: 19449329, 23431156, 26282667, 40994429, 40796363.