Unresolved cancer mechanism: A microbiota-derived bile acid overcomes antibiotic-induced hyporesponsiveness to immune checkpoint therapy by enhancing

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Description

Literature-mined gap from: “A microbiota-derived bile acid overcomes antibiotic-induced hyporesponsiveness to immune checkpoint therapy by enhancing CD8 (+) T cell antitumor immunity” (Li W et al., bioRxiv 2026; PMID 42039389). The paper signals unresolved mechanistic uncertainty in a cancer context.

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