Which specific BDNF promoters are targeted by sulforaphane-induced histone acetylation?

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Description

The study shows sulforaphane increases acetylated histones at BDNF promoters but doesn’t specify which of the multiple BDNF promoters are affected. Understanding promoter specificity is crucial for targeted therapeutic development and predicting tissue-specific effects.

Gap type: unexplained_observation Source paper: Sulforaphane epigenetically enhances neuronal BDNF expression and TrkB signaling pathways. (None, None, PMID:27735126)

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